Patents Assigned to NOBL Laboratories, Inc.
  • Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
    Patent number: 5885823
    Abstract: A method for large scale cultivation and attenuation of L. intracellularis bacteria by inoculating cells with L. intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti-L. intracellularis vaccines are prepared from cultures grown in suspension. Diagnostic agents are also disclosed.
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: March 23, 1999
    Assignee: NOBL Laboratories, Inc.
    Inventors: Jeffrey P. Knittel, Michael B. Roof
  • Ileal symbiont intracellularis propagation in suspended host cells
    Patent number: 5714375
    Abstract: A method for large scale cultivation and attenuation of IS intracellularis bacteria by inoculating cells with IS intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti-IS intracellularis vaccines are prepared from attenuated strains. Diagnostic agents are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 3, 1998
    Assignee: NOBL Laboratories, Inc.
    Inventors: Jeffrey P. Knittel, Michael B. Roof