Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
January 19, 2016
Assignee:
Nocicepta LLC
Inventors:
Lawrence R. Toll, David C. Yeomans, Martin S. Angst, Daniel I. Jacobs
Abstract: The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
Type:
Grant
Filed:
July 27, 2010
Date of Patent:
October 8, 2013
Assignee:
Nocicepta LLC
Inventors:
Lawrence R. Toll, David C. Yeomans, Martin S. Angst, Daniel I. Jacobs