Abstract: The present invention relates to radioimmunoconjugates that are capable of upregulating expression of one or more antigens. The upregulated antigens can be the antigens that are targeted by the radioimmunoconjugates or different antigens expressed on the same cells. The present invention also relates to methods of treating cancer and diseases and disorders of the immune system by utilizing this enhanced expression of antigens.
Abstract: The present invention relates to a radioimmunoconjugate that binds human CD37. Pharmaceutical compositions and uses thereof for the treatment of cancer and in particular B cell malignancies are aspects of the present invention.
Type:
Grant
Filed:
December 9, 2013
Date of Patent:
June 7, 2016
Assignee:
Nordic Nanovector AS
Inventors:
Roy H. Larsen, Jostein Dahle, Øyvind S. Bruland
Abstract: The present invention relates to a radioimmunoconjugate that binds human CD37. Pharmaceutical compositions and uses thereof for the treatment of cancer and in particular B cell malignancies are aspects of the present invention.
Type:
Application
Filed:
December 9, 2013
Publication date:
May 29, 2014
Applicant:
Nordic Nanovector AS
Inventors:
Roy H. Larsen, Jostein Dahle, Øyvind S. Bruland
Abstract: The present invention relates to a radioimmunoconjugate that binds human CD37. Pharmaceutical compositions and uses thereof for the treatment of cancer—and in particular B-cell malignancies—are aspects of the present invention.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
January 14, 2014
Assignee:
Nordic Nanovector AS
Inventors:
Roy H. Larsen, Jostein Dahle, Øyvind S Bruland
Abstract: The present invention relates to a radioimmunoconjugate that binds human CD37. Pharmaceutical compositions and uses thereof for the treatment of cancer—and in particular B-cell malignancies—are aspects of the present invention.
Type:
Application
Filed:
January 28, 2011
Publication date:
November 29, 2012
Applicant:
NORDIC NANOVECTOR AS
Inventors:
Roy H. Larsen, Jostein Dahle, Øyvind S. Bruland