Abstract: A method for the filtration of a fluid applying a certain preferred setting of one or more process parameters (e.g. a minimal concentration of coagulants) while maintaining desirable process performance by regulating the initial filtration resistance. This is achieved by a feedback controller. Applying the invention on in-line coagulation during membrane filtration has shown, that the initial resistance of the last filtration before the chemical cleaning phase can be controlled within an accuracy of approximately 3% (of the total resistance) or 9% (of the fouling resistance). Compared to current dosing strategy, a significant reduction in coagulant consumption can be achieved.