Abstract: The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
Type:
Application
Filed:
February 10, 2011
Publication date:
November 17, 2011
Applicant:
Normoxys
Inventors:
Yves Claude NICOLAU, Jean-Marie LEHN, Konstantina FYLAKTAKIDOU, Ruth GREFERATH