Abstract: The disclosure provides methods and apparatus for producing 3-hydroxypropionic acid or a salt thereof, for removing 3-hydroxypropionic acid from aqueous solution (e.g., aqueous broth), and for using it to make various chemicals.
Type:
Grant
Filed:
June 3, 2021
Date of Patent:
February 21, 2023
Assignee:
Noroo IC Co., Ltd.
Inventors:
Jeung Yeop Shim, Ki Soo Park, Ashok Somasundar, Sung Hoon Park
Abstract: The disclosure provides methods and apparatus for producing 3-hydroxypropionic acid or a salt thereof, for removing 3-hydroxypropionic acid from aqueous solution (e.g., aqueous broth), and for using it to make various chemicals.
Type:
Grant
Filed:
April 24, 2020
Date of Patent:
January 31, 2023
Assignee:
Noroo IC Co., Ltd.
Inventors:
Jeung Yeop Shim, Ki Soo Park, Ashok Somasundar, Sung Hoon Park
Abstract: The disclosure provides methods and apparatus for producing 3-hydroxypropionic acid or a salt thereof, for removing 3-hydroxypropionic acid from aqueous solution (e.g., aqueous broth), and for using it to make various chemicals.
Type:
Grant
Filed:
October 25, 2018
Date of Patent:
July 13, 2021
Assignee:
Noroo IC Co., Ltd.
Inventors:
Jeung Yeop Shim, Ki Soo Park, Ashok Somasundar, Sung Hoon Park
Abstract: The present invention relates to a promoter system inducing expression of 3-hydroxypropionic acid (3-HP) and a method of biologically producing 3-HP using the same. To improve production of 3-HP in a biological manner, continuous synthesis of new enzymes having enzyme activity is necessary. As a result of screening 3-HP reactive transcription regulators and 3-HP reactive promoters from several microorganisms including Pseudomonas denitrificans, it was confirmed that the transcriptions regulations and promoters are composed of LysR proteins and particular gene nucleotide sequences binding to the LysR proteins. Therefore, the 3-HP inducible system is expected to be effectively used to regulate 3-HP metabolic pathways.
Type:
Grant
Filed:
September 11, 2020
Date of Patent:
March 30, 2021
Assignees:
NOROO IC Co., Ltd., NOROO R&C CO., LTD.
Abstract: The present invention relates to a promoter system inducing expression of 3-hydroxypropionic acid (3-HP) and a method of biologically producing 3-HP using the same. To improve production of 3-HP in a biological manner, continuous synthesis of new enzymes having enzyme activity is necessary. As a result of screening 3-HP reactive transcription regulators and 3-HP reactive promoters from several microorganisms including Pseudomonas denitrificans, it was confirmed that the transcriptions regulations and promoters are composed of LysR proteins and particular gene nucleotide sequences binding to the LysR proteins. Therefore, the 3-HP inducible system is expected to be effectively used to regulate 3-HP metabolic pathways.
Type:
Application
Filed:
September 11, 2020
Publication date:
December 31, 2020
Applicants:
NOROO IC Co., Ltd., NOROO R&C CO., LTD.
Abstract: The present invention relates to a promoter system inducing expression of 3-hydroxypropionic acid (3-HP) and a method of biologically producing 3-HP using the same. To improve production of 3-HP in a biological manner, continuous synthesis of new enzymes having enzyme activity is necessary. As a result of screening 3-HP reactive transcription regulators and 3-HP reactive promoters from several microorganisms including Pseudomonas denitrificans, it was confirmed that the transcriptions regulations and promoters are composed of LysR proteins and particular gene nucleotide sequences binding to the LysR proteins. Therefore, the 3-HP inducible system is expected to be effectively used to regulate 3-HP metabolic pathways.
Type:
Grant
Filed:
June 13, 2016
Date of Patent:
October 20, 2020
Assignees:
NOROO IC CO., LTD., NOROO R&C CO., LTD.