Patents Assigned to North Carolina State University
  • Patent number: 12106470
    Abstract: An ultrasound system and method are provided for detecting lesions and/or abnormalities in a heterogeneous medium. An array of ultrasound transducer elements configured to emit ultrasound signals and to receive backscattered ultrasound signals. A processor performs a lesion detection algorithm that processes the backscattered ultrasound signals to obtain an Inter-element Response Matrix (IRM), splits the IRM into a plurality of sub-IRMs corresponding to subsets of the ultrasound transducer elements, and then performs additional processing that includes performing a depression detection algorithm to identify one or more lesions and/or abnormalities.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: October 1, 2024
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Marie Muller, Thomas Egan, Kaustav Mohanty
  • Patent number: 12098481
    Abstract: Strengthening the dry and wet tenacity of regenerated cellulosic fibers can be performed through the addition of an aldaric acid, such as (but not limited to) glucaric acid. In some embodiments, regenerated cellulosic fibers that include an aldaric acid or a salt thereof, produced by the disclosed methods are also described. The produced fibers have advantageous properties due at least in part to the inclusion of the aldaric acid.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: September 24, 2024
    Assignee: North Carolina State University
    Inventors: Ericka N. Ford, Ryan Dwyer, Hannah Dedmon
  • Patent number: 12091718
    Abstract: The present disclosure relates to high-throughput detection of polyketides using genetically encoded biosensors.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: September 17, 2024
    Assignee: North Carolina State University
    Inventors: Gavin J. Williams, Christian Kasey, Yiwei Li
  • Patent number: 12094932
    Abstract: A power device includes a packaged semiconductor switch containing first and second series-connected insulated-gate transistors, first and second control terminals electrically connected to the first and second insulated-gate transistors, respectively, first and second current carrying terminals electrically connected to the first and second insulated-gate transistors, respectively, and a voltage-monitoring terminal electrically connected to an internal node shared by first and second current carrying regions within the first and second insulated-gate transistors, respectively. The first and second control terminals can be electrically connected to a gate of the first insulated-gate transistor and a gate of the second insulated-gate transistor, respectively; and the first and second current carrying terminals can be electrically connected to a source of the first insulated-gate transistor and a drain (or collector) of the second insulated-gate transistor.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: September 17, 2024
    Assignee: North Carolina State University
    Inventor: Bantval Jayant Baliga
  • Patent number: 12087489
    Abstract: Various examples are provided related to transformer designs that offer very high isolation while maintaining high coupling between the windings. In one example, an isolation transformer includes a first excitation coil wound around a first core and a second excitation coil wound about a second core. The second core is electrically separated from the first core by a high resistivity magnetic material or a non-conductive material. The first and second cores can include corresponding core segments arranged in a trident geometry or a quindent geometry. The core segments can align when the first excitation coil is inserted into a void of the second excitation coil. The isolation transformer designs are mechanically separable which can result in safe, energized, plug operations.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: September 10, 2024
    Assignees: NORTH CAROLINA STATE UNIVERSITY, U.S. DEPARTMENT OF ENERGY
    Inventors: Richard Byron Beddingfield, Subhashish Bhattacharya, Tsz Sing Wong, Paul Ohodnicki
  • Patent number: 12076289
    Abstract: An exoskeleton wearable on a body of a human having two legs, the exoskeleton comprising a first HAA joint and a second HAA joint to assist the human with leg abduction and adduction movements that are parallel to a frontal plane, each of the first and the second HAA joints having an actuator, each actuator including a motor and a clutch. The exoskeleton further comprises a sensor system for measuring a combined center of mass of the human and the exoskeleton in the frontal plane and a step width of the human in the frontal plane. The exoskeleton further comprises a controller that outputs adjustment angles for each of the first and the second HAA joints based on the center of mass and the step width. The first and the second HAA joints are respectively rotated based on the respective output adjustment angles.
    Type: Grant
    Filed: September 22, 2018
    Date of Patent: September 3, 2024
    Assignee: North Carolina State University
    Inventors: He Huang, Ting Zhang
  • Patent number: 12077886
    Abstract: Mosquito resistant textiles and garments are provided that demonstrate resistance to mosquito bites without the use of pesticides or chemicals. The textiles and garments provide 90% or more resistance to mosquito bite resistance.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: September 3, 2024
    Assignee: North Carolina State University
    Inventors: Marian G. McCord, Richard Michael Roe, Charles S. Apperson, Andre J. West, Emiel A. DenHartog
  • Patent number: 12070052
    Abstract: The presently disclosed subject matter is directed to a method of extracting bioactive agents from biomass using continuous microwave-assisted extraction. The disclosed method includes contacting the biomass with a solvent and optionally homogenizing the biomass. Then blending the biomass and the solvent and continuously passing the biomass though one more microwave assisted extraction units, thereby exposing the biomass to microwave energy. The solvent is separated from the biomass, where the separated solvent is the bioactive agent.
    Type: Grant
    Filed: July 14, 2022
    Date of Patent: August 27, 2024
    Assignees: SinnovaTek, Inc., North Carolina State University
    Inventors: Michael Druga, Amanda Vargochik, Josip Simunovic
  • Publication number: 20240271156
    Abstract: Provided are expression cassettes that can be used to express proteins in plants. In some embodiments, the expression cassettes include polynucleotides that encode polypeptides that are at least 96% identical to SEQ ID NO: 2 operably linked to a promoter and a transcription terminator and optionally a tag sequence. Also provided are recombinant vectors, cells, and transgenic plants, progeny, and seeds that include the presently disclosed expression cassettes, and methods for using the disclosed expression cassettes to alter geminivirus resistance and suppress virus-induced leaf chlorosis, leaf curling, or both in plants.
    Type: Application
    Filed: September 6, 2022
    Publication date: August 15, 2024
    Applicant: North Carolina State University
    Inventors: Jose Trinidad Ascencio-Ibanez, Linda K. Hanley-Bowdoin, Wei Shen
  • Patent number: 12060437
    Abstract: The present invention is directed to an antibody that specifically binds an IgE receptor and methods of its use.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: August 13, 2024
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Bruce Hammerberg, Sitka Eguiluz-Hernandez
  • Patent number: 12053523
    Abstract: Disclosed herein are methods of treating/inhibiting/reducing a non-immunogenic cancer in a subject or inducing blockade inhibitor susceptibility (such as, for example, PD-1/PDLI, CTLA-4/B7-1/2, and/or CD47/SIRPa inhibitor susceptibility) in a tumor in a subject with a cancer, said methods comprising administering to the subject a hydrogel matrix comprising a chemotherapeutic agent (including, but not limited to gemcitabine) and a blockade inhibitor (including, but not limited to a PD-1/PD-LI blockade inhibitor, such as, for example nivolumab, pembrolizumab, pidilizumab, atezolizumab, avelumab, durvalumab, and BMS-936559; a CTLA-4/B7-1/2 inhibitor such as, for example, Ipilimumab; and/or a CD47/SIRPa inhibitor such as, for example Hu5F9-G4, CVI, B6H12, 2D3, CC-90002, and TTI-621).
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: August 6, 2024
    Assignee: North Carolina State University
    Inventors: Zhen Gu, Chao Wang
  • Publication number: 20240246075
    Abstract: Devices, systems, and methods for characterizing material samples. In one aspect, a device for characterizing a sample includes a substrate configured for receiving a sample thereon; an optical fiber probe comprising a first end positioned near the sample and a second end that is bifurcated to include one or more first fiber configured for connection to a first light emitting device and one or more second fiber configured for connection to a spectrometer; a reflectance module coupled to the substrate; and a second light emitting device positioned near the sample. The optical fiber probe is configured for selectively obtaining at the spectrometer both a reflectance absorbance measurement of the sample associated with the first light emitting device and a photoluminescence measurement of the sample associated with the second light emitting device.
    Type: Application
    Filed: August 21, 2023
    Publication date: July 25, 2024
    Applicant: North Carolina State University
    Inventors: Aram Amassian, Nathaniel R. Woodward, Mihirsinh Chauhan, Boyu Guo
  • Patent number: 12039618
    Abstract: A method, system, and device for controlling an energy storage device are provided. The method includes determining an operating schedule for the energy storage device based on at least an initial cost. The initial cost is a function of at least a load profile and a power production profile of at least one renewable energy source associated with the energy storage device. The operating schedule is for a predetermined period. The method further includes determining an updated cost based on at least the operating schedule, identifying an operating mode from a plurality of operating modes for a predetermined operating period based on the updated cost and the operating schedule; and operating using the operating mode for the predetermined operating period.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: July 16, 2024
    Assignees: TOTAL SOLAR INTERNATIONAL, NORTH CAROLINA STATE UNIVERSITY
    Inventors: Gonzague Henri, Ning Lu
  • Publication number: 20240226950
    Abstract: Spin coating systems and methods. In one aspect, a spin coater assembly is provided. The spin coater assembly includes a spinner configured for receiving a substrate thereon, a plurality of material dispensers, an arm assembly configured to selectively position one of the plurality of material dispensers over the substrate, and a controller in communication with each of the spinner, the plurality of material dispensers, and the arm assembly.
    Type: Application
    Filed: August 21, 2023
    Publication date: July 11, 2024
    Applicants: North Carolina State University, North Carolina State University
    Inventors: Aram AMASSIAN, Nathaniel R. WOODWARD, Boyu GUO
  • Patent number: 12018414
    Abstract: A warp knitted fabric formed by a warp knitting machine includes a first knitted portion formed using a first knitting sequence in a machine direction, the first knitted portion formed of a set of continuous textile strands, and a second knitted portion formed of the set of continuous textile strands using a second knitting sequence in the machine direction, the second knitted portion comprising at least two strips extending lengthwise in the machine direction and detached from one another along their lengthwise edges. The first knitted portion and the second knitted portion alternate sequentially in the machine direction. The second knitting sequence differs from the first knitting sequence in that at least one cross connecting stitch is dropped to form the at least two strips.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: June 25, 2024
    Assignees: Duke University, North Carolina State University
    Inventors: Howard Levinson, James Brian Davis, Don Ward, Jon Rust
  • Patent number: PP35881
    Abstract: A new and distinct cultivar of Ligustrum plant named ‘NCLJ1’ is disclosed, characterized rounded upright habit, white flowers, glossy evergreen foliage, and no apparent female fertility. The new variety is a Ligustrum, typically produced as an outdoor ornamental plant.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: June 25, 2024
    Assignee: North Carolina State University
    Inventors: Thomas Green Ranney, Andra Windorf Nus, Irene Palmer, Nathan P. Lynch
  • Patent number: PP35913
    Abstract: A new and distinct cultivar of x Pyracomeles plant named ‘NCXP2’ is disclosed, characterized by abundant white flowers with showy red fruit. Plants have compact, rounded habits, and glossy green foliage. The new variety is an x Pyracomeles, typically produced as an outdoor ornamental plant.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: July 2, 2024
    Assignee: North Carolina State University
    Inventors: Thomas Green Ranney, Andra Windorf Nus, Irene Palmer, Nathan P. Lynch
  • Patent number: PP36009
    Abstract: A new and distinct variety of Cercis plant, referred to by its cultivar name, ‘NC2017-92’, is disclosed. The new variety is characterized by its light, purple-colored flowers. The new variety is also characterized by its small and gold-colored foliage. A moderately slow growing, highly branched and compact growth habit is displayed.
    Type: Grant
    Filed: December 28, 2023
    Date of Patent: July 16, 2024
    Assignee: North Carolina State University
    Inventors: Dennis James Werner, Leanne M. Kenealy Atkins
  • Patent number: PP36029
    Abstract: A new and distinct variety of Cercis plant, referred to by its cultivar name, ‘NC2017-113’, is disclosed. The new variety is characterized by its white-colored flowers. The new variety is also characterized by its small, thick, glossy, and green-colored foliage. A moderately slow growing and compact growth habit is displayed.
    Type: Grant
    Filed: December 28, 2023
    Date of Patent: July 23, 2024
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Dennis James Werner, Leanne M. Kenealy Atkins
  • Patent number: PP36033
    Abstract: ‘XSA 11377’ is a new St. Augustinegrass cultivar that is fast to establish, has good levels of shade and drought tolerances, and has superior turf quality. It is distinguishable from other cultivars by its medium-fine texture, aggressive stoloniferous growth, improved sod strength, and improved shade tolerance. ‘XSA 11377’ shows gray leaf spot and chinch bug tolerance, and maintains above average turf quality under normal management practices. ‘XSA-11377’ is also genetically distinct from other St. Augustinegrass cultivars currently in the marketplace known to the Inventor.
    Type: Grant
    Filed: June 6, 2023
    Date of Patent: July 23, 2024
    Assignee: North Carolina State University
    Inventor: Susana Milla-Lewis