Patents Assigned to North Carolina State University
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Patent number: 11827722Abstract: Mechanically strong, biodegradable and reusable aerogels are disclosed, which can be made with a cross-linked cellulose ester, and which exhibit a low density and high porosity. The aerogels disclosed herein may be used as sorbent materials and can be modified with a hydrophobic and/or oleophilic agent.Type: GrantFiled: June 23, 2021Date of Patent: November 28, 2023Assignee: North Carolina State UniversityInventors: Anurodh Tripathi, Saad A. Khan, Orlando J. Rojas, Gregory N. Parsons, Jeremy Kenneth Steach, Jos Simon de Wit, S. M. Bedarul Islam, Jacob Donald Goodrich
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Patent number: 11826358Abstract: Disclosed herein are compositions and methods for delivering adipose tissue browning agents and/or fat modulating agents.Type: GrantFiled: September 13, 2018Date of Patent: November 28, 2023Assignees: NORTH CAROLINA STATE UNIVERSITY, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventors: Zhen Gu, Yuqi Zhang, Li Qiang
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Patent number: 11819702Abstract: Disclosed herein are perovskite materials and methods of making an use thereof.Type: GrantFiled: March 4, 2021Date of Patent: November 21, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Paul A. Maggard, Jr., Shaun O'Donnell, Jacob L. Jones
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Patent number: 11824461Abstract: Various examples are provided related to modular multilevel converter (MMC) scale-up control methodologies which can be applied for MV and HV DC applications. In one example, an MMC includes first and second legs each with submodule (SM) groups connected in series, where each SM group includes a plurality of SMs; local group controllers that can control a corresponding SM group; and a central controller that can control output voltage of the MMC via the local group controllers. The local group controllers can provide capacitor voltage balancing (CVB) control of corresponding SM groups.Type: GrantFiled: June 24, 2021Date of Patent: November 21, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Subhashish Bhattacharya, Mohammed Alharbi
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Patent number: 11824403Abstract: Various examples are provided related to machines utilizing heavy rare earth (HRE) free permanent magnets. In one example, a rotor assembly including a rotor core having a plurality of rotor slots and magnets positioned within the plurality of rotor slots. At least a portion of the magnets are free of heavy rare earth (HRE) elements. The magnets can include a combination HRE segments and HRE-free segments or can be free of HRE elements. The rotor assembly can be included in an electric machine such as, e.g., a permanent magnet (PM) machine.Type: GrantFiled: April 2, 2021Date of Patent: November 21, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Md. Sariful Islam, Iqbal Husain
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Patent number: 11813592Abstract: Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region such as CaMnO3, BaMnO3??, SrMnO3??, Mn2SiO4, Mn2MgO4??, La0.8Sr0.2O3??, La0.8Sr0.2FeO3??, Ca9Ti0.1Mn0.9O3??, Pr6O11??, manganese ore, or a combination thereof; and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. The outer shell can include, for example a salt selected such as Li2WO4, Na2WO4, K2WO4, SrWO4, Li2MoO4, Na2MoO4, K2MoO4, CsMoO4, Li2CO3, Na2CO3, K2CO3, or a combination thereof.Type: GrantFiled: June 14, 2018Date of Patent: November 14, 2023Assignee: North Carolina State UniversityInventors: Fanxing Li, Luke Michael Neal, Yunfei Gao, Seif Yusuf, Ryan Dudek
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Patent number: 11813352Abstract: A composition comprising a glucose-responsive charge-switchable polymer is described. In the absence of glucose or under normoglycemic conditions, the positively charged polymer can be complexed with negatively charged therapeutic agents, such as insulin. Under hyperglycemic conditions, the positive charge of the polymer is reduced, and the polymer/therapeutic agent complex can disassemble, allowing the therapeutic agent to be released. Pharmaceutical compositions, nanoparticles, and microneedle arrays of the polymer and/or polymer/therapeutic agent complex and methods of treating diabetes are also described.Type: GrantFiled: November 20, 2018Date of Patent: November 14, 2023Assignee: North Carolina State UniversityInventors: Zhen Gu, Jinqiang Wang
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Patent number: 11807859Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.Type: GrantFiled: March 1, 2022Date of Patent: November 7, 2023Assignees: North Carolina State University, University of Kentucky Research FoundationInventors: Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano
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Patent number: 11802207Abstract: Methods of preparing a lignocellulosic biomass-based thermoplastic composition are described. In some embodiments, the method comprises: (a) preparing a mixture of solids comprising lignocellulosic biomass, a meltable solvent and a polyester; and (b) melt-compounding said mixture of solids; thereby preparing a lignocellulosic biomass-based thermoplastic composition. Fibers produced by the methods are also described, as are yarns and fabrics comprising the fibers.Type: GrantFiled: December 30, 2021Date of Patent: October 31, 2023Assignee: North Carolina State UniversityInventors: Ericka N. Ford, Manik Chandra Biswas
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Patent number: 11795467Abstract: The present invention provides nucleic acids encoding transcription factors and methods of using these nucleic acids to modulate nicotine production in plants and to produce plants having modulated nicotine production.Type: GrantFiled: April 6, 2022Date of Patent: October 24, 2023Assignee: North Carolina State UniversityInventors: Rongda Qu, Bingwu Wang
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Patent number: 11786477Abstract: Disclosed herein are low density particles comprising polymerized fibrin that are micrometer or nanometer sized in diameter. The particles can further include at least one therapeutic agent. The particles may be used to treat wounds, by administration directly or systemically to the site of the wound. Exemplary wounds that may be treated with the fibrin particles include a trauma wound, a surgical wound, a burn wound, or an ulcer wound. Also disclosed herein are methods for preparing the particles using a shearing process.Type: GrantFiled: December 3, 2018Date of Patent: October 17, 2023Assignee: North Carolina State UniversityInventors: Ismaeel Muhamed, Ashley C. Brown, Frances S. Ligler
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Patent number: 11787152Abstract: A composite sheet comprising two or more layers is described where the degree of abrasiveness of can be controlled. The sheet can comprise partially or wholly biodegradable or compostable materials or blends thereof. Methods of preparing the composite sheets are also described.Type: GrantFiled: December 12, 2019Date of Patent: October 17, 2023Assignee: North Carolina State UniversityInventor: Behnam Pourdeyhimi
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Patent number: 11788790Abstract: Devices, systems, and methods for drying a bulk waste product, such as animal waste, having a moisture content of 95% or more water can include a trough configured to receive the bulk waste product and to dispense it in a form suitable for convective drying, one or more conveyors having an air-permeable conveyor belt, each conveyor receiving the waste product from the trough and transporting the waste product along a transport path; and one or more air moving devices (AMDs) that pass air through the air-permeable conveyor belt and across the waste product as it is transported along the transport path to transform the bulk waste product into a dried waste product having a moisture content of about 5% to about 20%, inclusive.Type: GrantFiled: February 21, 2020Date of Patent: October 17, 2023Assignee: North Carolina State UniversityInventors: Christopher B. Hopkins, Joseph L. Stuckey
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Patent number: 11786713Abstract: Disclosed herein are microneedle devices, kits comprising the microneedle devices, and methods of using the microneedle devices. Specifically, disclosed is a device for transport of a material across a biological barrier of a subject comprising: a plurality of microneedles each having a base end and a tip, with at least one pathway disposed at or between the base end and the tip; a substrate to which the base ends of the microneedles are attached or integrated; and at least one reservoir which is in connection with the base ends of the microneedles array, wherein the reservoir comprises an agent delivery system, wherein the agent delivery system comprises an agent to be transported across the biological barrier, or a means for producing an agent to be transported across the biological barrier, and a means for detecting a physiological signal from the recipient.Type: GrantFiled: March 30, 2021Date of Patent: October 17, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Zhen Gu, Yanqi Ye
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Patent number: 11785995Abstract: An insect-proof, form-fitting undergarment is provided having top and bottom parts formed of selected breathable materials and having omnidirectional stretch properties, and which top and bottom parts may be securely joined at the waist to prevent insect entry. A superfine knitted fabric is utilized to prevent insect bites.Type: GrantFiled: June 9, 2020Date of Patent: October 17, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Andre J. West, Marian G. McCord, Charles S. Apperson, Richard Michael Roe, Emiel A. DenHartog
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Patent number: 11790464Abstract: An aggregated distribution system includes an HVAC controller, a battery controller, and an aggregated data management engine. The aggregated data management engine is configured to retrieve an HVAC energy usage profile and retrieve a battery energy usage profile. The aggregated distribution system also includes distribution engine configured to forward a first set of HVAC dual variables and forward a first set of battery dual variables to a first neighboring unit of the aggregated distribution system, receive one or more additional sets of HVAC dual variables and one or more additional sets of battery dual variables from one or more neighboring units of the aggregated distribution system, update the HVAC energy usage profile with the one or more additional sets of HVAC dual vehicles and update the battery energy usage profile with the one or more additional sets of battery dual vehicles.Type: GrantFiled: September 6, 2017Date of Patent: October 17, 2023Assignees: TOTAL SOLAR INTERNATIONAL, NORTH CAROLINA STATE UNIVERSITYInventors: Mo-Yuen Chow, Alberto Castelo Becerra, Wente Zeng
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Publication number: 20230324822Abstract: Disclosed are methods and systems for solid phase transfer of a reagent to a substrate. In some embodiments, the method comprises providing at least a first composition comprising a solid phase, wherein the solid phase comprises a reagent; and dispensing a first sample from the first composition onto a first coordinate on a substrate, whereby the first reagent is transferred to the substrate from the solid phase.Type: ApplicationFiled: August 25, 2021Publication date: October 12, 2023Applicant: North Carolina State UniversityInventors: Albert Jun Qi Keung, James M. Tuck, Kyle Tomek
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Patent number: 11778965Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.Type: GrantFiled: September 22, 2021Date of Patent: October 10, 2023Assignees: North Carolina State University, University of Kentucky Research FoundationInventors: Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano
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Patent number: 11784641Abstract: Various examples are provided related to supercascode power switches that can be used in, e.g., HV and MV applications. This disclosure introduces a cascaded supercascode (CSC) power switch which can include a series of unit supercascode (USC) circuits; a control switch coupled in series with the series of USC circuits; and an external balancing network coupled to each of the n USC circuits. The series has a plurality of USC circuits, with each of the USC circuits including first and second switches coupled in series and an internal balancing network coupled across the first and second switches. A source of each of the USC circuits is a source of the first switch. The internal balancing network can include a capacitor connected between a gate of the second switch and the source of the first switch and a diode connected in parallel with the capacitor.Type: GrantFiled: January 15, 2022Date of Patent: October 10, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Utkarsh Mehrotra, Douglas C. Hopkins
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Patent number: 11776784Abstract: Various examples are provided related to direct current circuit breakers and their control methods. In one example, among others, a hybrid direct current circuit breaker (DCCB) includes an ultrafast mechanical switch (UFMS) connected in series with a commutating switch (CS) or auxiliary circuit breaker (ACB); a main breaker (MB) including a series of ? semiconductor switching stages in parallel with the UFMS and CS or ACB; and control circuitry that can turn off individual switching stages in a defined order in response to opening contacts of the UFMS. The switching stages can be turned off based upon a dielectric strength across the contacts as they open. In another example, a method includes opening contacts of an UFMS connected in series with a CS or ACB; and turning off individual switching stages of a series of ? semiconductor switching stages connected across the UFMS and the CS or ACB.Type: GrantFiled: September 21, 2019Date of Patent: October 3, 2023Assignee: NORTH CAROLINA STATE UNIVERSITYInventors: Chang Peng, Iqbal Husain, Qin Huang, Landon K. Mackey