Patents Assigned to NORTHWEST A&F UNIVERSITY
  • Patent number: 11920142
    Abstract: The use of a negative regulator AtRTP5 for increasing the plant resistance to Phytophthora is disclosed. The AtRTP5 gene negatively regulates the plant resistance to Phytophthora by interfering with a plant hormone immune signaling pathway. The AtRTP5 gene has a nucleotide sequence shown as SEQ ID NO: 1 or a homologous sequence having more than 50% homology with the sequence. The use of a protein encoded by a negative regulator AtRTP5 for increasing the plant resistance to Phytophthora is also disclosed. The plant resistance to Phytophthora is enhanced by reducing the expression of the protein encoded by the AtRTP5 gene with genetic engineering. The protein has an amino acid sequence shown as SEQ ID NO: 2 or a homologous sequence having more than 50% homology with the sequence.
    Type: Grant
    Filed: September 12, 2020
    Date of Patent: March 5, 2024
    Assignee: Northwest A&F University
    Inventors: Weixing Shan, Weiwei Li
  • Patent number: 11920143
    Abstract: The present disclosure discloses an AtPPR1 gene (negative regulatory factor) for Phytophthora resistance and homologous genes thereof, involving an AtPPR1 gene and a protein encoded by the AtPPR1 gene. The AtPPR1 gene has a nucleotide sequence of SEQ ID NO:6, and the protein encoded by the AtPPR1 gene has an amino acid sequence of SEQ ID NO:7. A function of the AtPPR1 gene of the present disclosure to improve Phytophthora resistance of plants can be used for the selective breeding of Phytophthora-resistant varieties. As a new type of negative immunoregulatory factor in plants, AtPPR1 negatively regulates the resistance of plants to Phytophthora by interfering with downstream signal transduction of endogenous jasmonic acid (JA) and salicylic acid (SA) and ROS signals in plants.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: March 5, 2024
    Assignee: NORTHWEST A&F UNIVERSITY
    Inventors: Weixing Shan, Yang Yang
  • Patent number: 11680062
    Abstract: Disclosed are 3,4-methylenedioxyphenylimidazolylethanonexime ether derivatives, a preparation method and use thereof, and a drug for the treatment of Alzheimer's disease, which relates to the technical field of preparation of acetophenone oxime ether compounds. The (Z)-3,4-methylenedioxyphenylimidazolylethanonexime ether derivatives provided by the present disclosure show a significant effect on the inhibition of NO production, with an EC50 of 2.07-5.41 ?mol/L. Compared with the positive control group of quercetin (with an EC50 of 9.56 ?mol/L) and oxiconazole (with an EC50 of 13.5 ?mol/L), the inhibitory effect is stronger without significant cytotoxicity (cell viability >90%), which can be used to prepare drugs for the treatment of Alzheimer's disease.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: June 20, 2023
    Assignee: NORTHWEST A & F UNIVERSITY
    Inventors: Jiangjiang Tang, Zhaoyuan Bian, Lanfang Huang, Bo Ren, Ping Xiang, Jinming Gao
  • Publication number: 20230105315
    Abstract: A steroidal piperidone derivative, a synthesis method, and a use thereof are provided. The steroidal piperidone derivative has a chemical structure shown in general formula (1) or general formula (2), where R is any one selected from the group consisting of alkyl, phenyl, substituted phenyl, and a heterocycle. In the synthesis method of the steroidal piperidone derivative, dehydroepiandrosterone (DHEA) is used as a basic raw material to prepare the steroidal piperidone derivative of the present disclosure through a series of reactions. A product prepared by the synthesis method has a high yield and is easily separated, and thus the synthesis method is the optimal method for preparing the steroidal piperidone derivative of the present disclosure. The present steroidal piperidone derivative exhibits prominent toxic activity against sucking pests, such as aphids, spider mites, rice planthoppers, and B. tabaci, and can be used for the control of a plant pest.
    Type: Application
    Filed: September 23, 2022
    Publication date: April 6, 2023
    Applicant: NORTHWEST A&F UNIVERSITY
    Inventors: Baojun SHI, Weiqi JIANG, Shichuang MA, Yuxiao HU, Qiangping WANG
  • Publication number: 20230058791
    Abstract: A method for simulating a development date based on a response mechanism and an adaptation mechanism of a crop to an environment, including: collecting crop phenology data observed at a research station; obtaining a day of year of a start date, a quantity of days, and an average temperature, in the development phase, based on the crop phenology data; obtaining a development rate based on the quantity of days in the development phase, where the development rate is a reciprocal of the quantity of days in the development phase; calculating a product of the average temperature and the day of year of the start date of the development phase; and obtaining a regression equation as an equation simulating the development date, through a linear regression algorithm, where the development rate serves as a dependent variable, and the average temperature and the product serve as regressors.
    Type: Application
    Filed: August 6, 2019
    Publication date: February 23, 2023
    Applicants: CHINESE ACADEMY OF METEOROLOGICAL SCIENCES, NORTHWEST A&F UNIVERSITY
    Inventors: Dingrong WU, Qiang YU, Peijuan WANG, Zhiguo HUO, Yanling SONG, Jianying YANG
  • Patent number: 11421764
    Abstract: The invention relates to mechanical engineering, and more particularly to a curved groove ball bearing mechanism, in which a pair of curved groove ball bearings without a retainer are symmetrically arranged to enable the conversion between the rotary motion and the reciprocating linear motion. The bearing mechanism includes an inner ring, a first outer ring, a second outer ring, a plurality of first steel balls and a plurality of second steel balls. The invention is capable of achieving the conversion between the rotary motion of the inner ring into the reciprocating linear motion of the first and second outer rings.
    Type: Grant
    Filed: December 29, 2019
    Date of Patent: August 23, 2022
    Assignee: Northwest A&F University
    Inventors: Kangquan Guo, Qunzhuo Li, Fang Gu
  • Publication number: 20220248595
    Abstract: The present disclosure relates to a precision seeding apparatus with recesses on a caterpillar for arranging and distributing seeds against bottoms of seed furrows. The apparatus includes a frame; the frame is provided with a seed box with a seed distribution opening; a caterpillar for transporting seeds capable of being connected with a drive mechanism is arranged in the seed box; a lower part of the caterpillar for transporting seeds corresponds to the position of the seed distribution opening; the caterpillar is provided with at least one column of recesses in a lengthwise direction of the caterpillar; each group of recesses is connected through a seed unloading ditch; the seed unloading ditch is formed into a ring in a lengthwise direction of the caterpillar for transporting seeds; a lower part of the caterpillar for transporting seeds is provided with a comb sheet.
    Type: Application
    Filed: February 8, 2022
    Publication date: August 11, 2022
    Applicants: Northwest A & F University, Beijing Guanghui Caizhi Management Consulting Co., Ltd.
    Inventors: Dong WANG, Wensheng Tian
  • Patent number: 11193418
    Abstract: The present invention relates to internal combustion engines, and discloses a double-cylinder internal combustion engine. The double-cylinder internal combustion engine of the present invention adopts a curved groove ball bearing mechanism to replace crank-connecting rod mechanisms since traditional internal combustion engines have a complicated structure, high material requirements, high processing difficulty, and the inertia effect and noises thereof are hard to be eliminated. Two inner rings of the curved groove ball bearing mechanism are fixedly connected, and a valve mechanism and an ignition mechanism are driven through a gear pair, so that the two sets of cylinders and pistons reciprocate in opposite directions to automatically balance reciprocating inertia thereof. Compared with the prior art, the present invention has simple motion forms which only consist of the rotary motion and the reciprocating motion, and low noises are produced.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: December 7, 2021
    Assignee: NORTHWEST A&F UNIVERSITY
    Inventors: Kangquan Guo, Junchang Zhang, Hongling Jin, MingFang Wu, ZhiJie Liu
  • Patent number: 11098282
    Abstract: A serum-free culture medium for in vitro maturation of bovine oocytes includes a Hepes-free M199 basal medium, fatty acid-free BSA, human menopausal gonadotrophin (HMG), 17?-estradiol, epidermal growth factor (EGF), L-cysteine, bFGF, Glutamax (100×), folic acid, cholic acid and CXCL12. A method of culturing bovine oocytes using such serum-free culture medium is provided.
    Type: Grant
    Filed: September 7, 2020
    Date of Patent: August 24, 2021
    Assignee: NORTHWEST A&F UNIVERSITY
    Inventors: Jingcheng Zhang, Yuemeng Huang, Min Zhang, Debao Wang, Yong Wang, Yong Zhang
  • Patent number: 10895281
    Abstract: The invention relates to universal machine parts, and more particularly to a curved groove ball bearing without a retainer, which can solve the problems in the prior at such as high pendulating frequency and small amplitude. For the bearing, an inner ring and an outer ring are respectively provided with a first curved groove and a second curved groove, where “peaks” and “valleys” of the first curved groove are respectively the same as those of the second curved groove in number. The second curved groove is filled with steel balls, and a retainer for fixing the relative positions of the steel balls is removed, increasing the amplitude and reducing the pendulating frequency.
    Type: Grant
    Filed: December 29, 2019
    Date of Patent: January 19, 2021
    Assignee: Northwest A&F University
    Inventors: Kangquan Guo, Yaohua Hu, Wenjing Zhang, Fang Gu, Mingfang Wu
  • Patent number: 10779555
    Abstract: The present invention discloses a method for efficiently and mildly reducing ovalbumin allergenicity. The present invention promotes the exposure of the ovalbumin allergenic site to the molecular surface by repeated freezing and thawing pretreatment, and combines transglycosylase and trypsinase for synergistic treatment to reduce the ovalbumin sugar chain and epitope to achieve the purpose of significantly reducing the allergenicity of ovalbumin and egg foods. Compared with other traditional methods such as high temperature and high pressure and other physical means to reduce egg allergenicity, the method significantly improves the specificity and effectiveness of egg desensitization, and minimizes the damage to the nutrition and quality of egg proteins, and is an efficient and mild egg desensitization method. The method has the prospects of being applied to the industrial development of low-allergenicity egg products.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: September 22, 2020
    Assignee: NORTHWEST A&F UNIVERSITY
    Inventors: Xiang Duan, Xuebo Liu, Yinying Tan, Ying Lan, Yutang Wang, Zhigang Liu, Chunxia Xiao, Lin Chen
  • Publication number: 20190357569
    Abstract: The present invention discloses a method for efficiently and mildly reducing ovalbumin allergenicity. The present invention promotes the exposure of the ovalbumin allergenic site to the molecular surface by repeated freezing and thawing pretreatment, and combines transglycosylase and trypsinase for synergistic treatment to reduce the ovalbumin sugar chain and epitope to achieve the purpose of significantly reducing the allergenicity of ovalbumin and egg foods. Compared with other traditional methods such as high temperature and high pressure and other physical means to reduce egg allergenicity, the method significantly improves the specificity and effectiveness of egg desensitization, and minimizes the damage to the nutrition and quality of egg proteins, and is an efficient and mild egg desensitization method. The method has the prospects of being applied to the industrial development of low-allergenicity egg products.
    Type: Application
    Filed: January 24, 2018
    Publication date: November 28, 2019
    Applicant: NORTHWEST A&F UNIVERSITY
    Inventors: Xiang DUAN, Xuebo LIU, Yinying TAN, Ying LAN, Yutang WANG, Zhigang LIU, Chunxia XIAO, Lin CHEN