Patents Assigned to Notox, Ltd.
  • Pharmaceutical compositions comprising tyrphostins
    Publication number: 20030013748
    Abstract: Compounds useful for countering undesired toxic effects to cells, tissues or organs having formula (I) wherein: Ar is a group of formulae (i) or (ii), n is O or, when Ar has formula (i) above, then n may also be 1, R is CN, —GC(S)NH2, —C(O)NHR3 or, when R1 is 4—NO2 and R2 is H or 3—OH, then R may also be a group of formulae (iii), (iv), (v), (vi) where R3 is H, phenyl, phenyl(lower alkyl) or pyridylmethyl; R1 and R2 are each independently H, OH, NO2 or, when R is CN, also CH3, F, or CF3, provided that both R1 and R2 are simultaneously H.
    Type: Application
    Filed: May 9, 2002
    Publication date: January 16, 2003
    Applicant: Notox Ltd.
    Inventors: Abraham Novogrodsky, Alexander Levitzki, Aviv Gazit
  • Pharmaceutical compositions comprising tyrphostins
    Patent number: 6426366
    Abstract: Compounds useful for countering undesired toxic effects to cells, tissues or organs having formula (I) wherein: Ar is a group of formulae (i) or (ii), n is 0 or, when Ar has formula (i) above, then n may also be 1, R is CN, —GC(S)NH2, —C(O)NHR3 or, when R1 is 4-NO2 add R2 is H or 3-OH, then R may also be a group of formulae (iii), (iv), (v), (vi) where R3 is H, phenyl, phenyl(lower alkyl) or pyridylmethyl; R1 and R2 are each independently H, OH, NO2 or, when R is CN, also CH3, F, or CF3, provided that both R1 and R2 are not simultaneously H.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: July 30, 2002
    Assignee: Notox, Ltd.
    Inventors: Abraham Novogrodsky, Alexander Levitzki, Aviv Gazit