Patents Assigned to NovaBiotics Limited
  • NAIL FORMULATIONS AND TREATMENT REGIMES
    Publication number: 20230301895
    Abstract: The invention relates to aqueous formulations for topical nail application. The invention also relates to compositions for use in the treatment of a fungal nail infection, the composition being applied over a defined period.
    Type: Application
    Filed: July 2, 2021
    Publication date: September 28, 2023
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O’NEIL, Derry MERCER
  • Microparticles comprising a sulphur-containing compound
    Patent number: 11369568
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: June 28, 2022
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Antimicrobial compositions with cysteamine
    Patent number: 11020414
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: June 1, 2021
    Assignee: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Cedric Charrier
  • Microparticles
    Patent number: 10905660
    Abstract: The present invention provides microparticles comprising a sulphur-containing compound, such as cysteamine, or a pharmaceutically acceptable salt, hydrate or ester thereof. Also provided is a composition comprising the microparticles and a stabilizing agent.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: February 2, 2021
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Antibiotic compositions comprising an antibiotic agent and cysteamine
    Patent number: 9782423
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: October 10, 2017
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Cedric Charrier
  • Topical formulation of arginine-rich cyclic antimicrobial peptides
    Patent number: 9518093
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: December 13, 2016
    Assignee: NOVABIOTICS LIMITED
    Inventor: Deborah O'Neil
  • Inhibition of Biofilm Organisms
    Publication number: 20160206575
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Application
    Filed: March 28, 2016
    Publication date: July 21, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Derry MERCER, Cedric CHARRIER
  • Peptides and their use
    Patent number: 9371363
    Abstract: The invention relates to peptides, and peptide variants thereof, in which substantially all of the amino acids in the amino sequence of said peptide are the same, for use as antibacterial agents.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 21, 2016
    Assignee: Novabiotics Limited
    Inventor: Deborah O'Neil
  • Cyclic Antimicrobial Peptides
    Publication number: 20160168203
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Application
    Filed: November 9, 2015
    Publication date: June 16, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'NEIL
  • Antimicrobial compositions with cysteamine
    Patent number: 9364491
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: June 14, 2016
    Assignee: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Cedric Charrier
  • Antimicrobial Compositions with Cysteamine
    Publication number: 20160158169
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Application
    Filed: February 11, 2016
    Publication date: June 9, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Cedric CHARRIER
  • Inhibition of biofilm organisms
    Patent number: 9339525
    Abstract: The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: May 17, 2016
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • USE
    Publication number: 20160106689
    Abstract: The present invention relates to compositions comprising cysteamine or a derivative thereof for use in treating infections caused by yeasts or moulds.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 21, 2016
    Applicant: NOVABIOTICS LIMITED
    Inventor: Deborah O'NEIL
  • Use of Cysteamine in Treating Infections caused by Yeasts/Moulds
    Publication number: 20160102052
    Abstract: The present invention relates to compositions comprising cysteamine or a derivative thereof for use in treating infections caused by yeasts or moulds.
    Type: Application
    Filed: September 22, 2015
    Publication date: April 14, 2016
    Applicant: Novabiotics Limited
    Inventors: Deborah O'NEIL, Vanessa DUNCAN
  • Treatment of bacterial infections with cyclic antimicrobial peptides
    Patent number: 9181303
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: November 10, 2015
    Assignee: NovaBiotics Limited
    Inventor: Deborah O'Neil
  • Peptides and their use
    Patent number: 9169290
    Abstract: The present invention relates to peptides for use as antifungal agents. The peptides comprise a sequence of 5 to 15 basic amino acids wherein substantially all of the amino acids in said sequence are the same.
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: October 27, 2015
    Assignee: NovaBiotics Limited
    Inventor: Deborah O'Neil
  • Composition
    Publication number: 20140357592
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Application
    Filed: August 15, 2014
    Publication date: December 4, 2014
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'NEIL, Cedric CHARRIER
  • Compounds and their use
    Patent number: 8901071
    Abstract: The present invention relates to peptides and their use in the treatment of microbial infections, in particular bacterial infections. In particular, the invention relates to peptides wherein at least 75% of the amino acids of the peptide are arginine and phenylalanine amino acids, at least 50% of the amino acids being arginine amino acids and at least 15% of the amino acids being phenylalanine amino acids.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: December 2, 2014
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Derry Mercer, Cedric Charrier
  • Polypeptides and Their Use
    Publication number: 20140155321
    Abstract: The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.
    Type: Application
    Filed: March 14, 2013
    Publication date: June 5, 2014
    Applicant: Novabiotics Limited
    Inventors: Deborah O'NEIL, Derry MERCER, Colin STEWART
  • Method of Establishing a Fungal Nail Infection
    Publication number: 20130109049
    Abstract: The present invention provides a method of infecting a nail fragment with a fungus, to form an infected nail fragment comprising at least 1×102 fungal colony forming units (cfu) per cm2 of the infected surface(s). There is also provided a method of assessing the efficacy of potential therapeutic compounds in the treatment or prevention of a fungal nail infection. The fungal nail infection may be a dermatophyte, a non-dermatophyte mould or a pathogen.
    Type: Application
    Filed: December 20, 2010
    Publication date: May 2, 2013
    Applicant: NOVABIOTICS LIMITED
    Inventors: Deborah O'Neil, Derry Mercer, Colin Stewart