Patents Assigned to NOVABONE PRODUCTS, LLC
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Patent number: 10646514Abstract: Methods for processing and or removing organic residuals and or impurities from a solgel-derived bioactive glass-ceramic and compositions comprising solgel-derived bioactive glass-ceramics processed using these methods, are described.Type: GrantFiled: April 4, 2017Date of Patent: May 12, 2020Assignee: NOVABONE PRODUCTS, LLCInventors: Chloƫ Goldbach, Gregory J. Pomrink, Roy Layne Howell, Meryem Demir
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Patent number: 10524916Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 15-45% CaO, 30-70% SiO2, 0-25% Na2O, 0-17% P2O5, 0-10% MgO and 0-5% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.Type: GrantFiled: June 5, 2017Date of Patent: January 7, 2020Assignee: NOVABONE PRODUCTS, LLCInventors: Qiang Jie, Jiang Chang, Weiming J. Gu, Jipin Zhong, Gregory J. Pomrink
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Patent number: 10143707Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof, which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.Type: GrantFiled: November 15, 2016Date of Patent: December 4, 2018Assignee: NOVABONE PRODUCTS, LLCInventors: Gregory J. Pomrink, Jipin Zhong, Zehra Tosun, Roy Layne Howell, Cecilia Cao
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Publication number: 20170354501Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 15-45% CaO, 30-70% SiO2, 0-25% Na2O, 0-17% P2O5, 0-10% MgO and 0-5% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.Type: ApplicationFiled: June 5, 2017Publication date: December 14, 2017Applicant: NOVABONE PRODUCTS, LLCInventors: Qiang Jie, Jiang Chang, Weiming J. Gu, Jipin Zhong, Gregory J. Pomrink
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Patent number: 9707079Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO2, 0-25% Na2O, 5-17% P2O5, 0-5% MgO and 0-1% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.Type: GrantFiled: May 27, 2016Date of Patent: July 18, 2017Assignee: NOVABONE PRODUCTS, LLCInventors: Jiang Chang, Weiming Gu, Jipin Zhong
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Patent number: 9498459Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.Type: GrantFiled: March 11, 2014Date of Patent: November 22, 2016Assignee: NOVABONE PRODUCTS, LLCInventors: Gregory J. Pomrink, Jipin Zhong, Zehra Tosun, Roy Layne Howell, Cecilia Cao
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Patent number: 9433704Abstract: A settable osteostimulative bone graft putty composition having a bioactive glass particulate component composed of a long-term and a short-term component; the long-term component having particle sizes greater than 90 micrometers and the short-term component having particle sizes less than 90 micrometers; the long-term component comprising about 60% to 90% of the bioactive glass osteostimulative particulate component dry weight and the short-term component comprising about 40% to 10%; a binder component having a calcium sulfate component and a calcium silicate component; the calcium sulfate component comprising about 35% to 50% of the binder component dry weight and the calcium silicate component comprising about 65% to 50%; the bioactive glass osteostimulative particulate component being about 20% to 60% of the total putty dry weight composition and the binder being about 80% to 40%; the bioactive glass particulate component and the binder component mixable in water to form the putty.Type: GrantFiled: March 6, 2008Date of Patent: September 6, 2016Assignee: NOVABONE PRODUCTS, LLCInventors: Jipin Zhong, David M. Gaisser
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Publication number: 20150366908Abstract: A composition including calcium salt and silica, wherein the silica is in the form of a silicate that is adsorbed onto the surface of the calcium salt, wherein the silica is not incorporated into the structure of the calcium salt, and wherein the composition is bioactive.Type: ApplicationFiled: September 1, 2015Publication date: December 24, 2015Applicant: NOVABONE PRODUCTS, LLCInventors: Gregory J. Pomrink, Cecilia A. Cao
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Patent number: 9198936Abstract: This invention relates to methods for producing a composite bone graft material that can regenerate bony defects in the body. The invention further relates to methods that allow for the production of bioactive glass particles used in the composite that have been surface treated to allow for the production of a highly porous composite that can hold significant amounts of body fluid or other molecules that will aid in the regenerative process. The method of surface treatment allows for the manufacture of a suitable implantable composite while retaining the unique osteostimulative properties that are associated with bioactive glass particles.Type: GrantFiled: February 28, 2014Date of Patent: December 1, 2015Assignee: NOVABONE PRODUCTS, LLCInventors: David C. Greenspan, Srinivas Katta
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Patent number: 9199032Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.Type: GrantFiled: December 16, 2014Date of Patent: December 1, 2015Assignee: NOVABONE PRODUCTS, LLCInventors: Dennis McBride, Joshua P. Clark, Richard Davis, Gregory J. Pomrink, Zehra Tosun, David C. Greenspan
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Patent number: 9199006Abstract: The present invention relates to combination products including bioactive glass and collagen as well as kits comprising the same.Type: GrantFiled: March 27, 2014Date of Patent: December 1, 2015Assignee: NOVABONE PRODUCTS, LLCInventors: Gregory J. Pomrink, Zehra Tosun, Cecilia A. Gao, Joshua Clark, David C. Greenspan
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Patent number: 9144629Abstract: Compositions including crosslinked collagen and bioactive glass having an average pore size of at least 100 microns and methods of preparation thereof.Type: GrantFiled: March 15, 2013Date of Patent: September 29, 2015Assignee: NOVABONE PRODUCTS, LLCInventors: Gregory J. Pomrink, Cecilia A. Cao, Joshua Clark, Zehra Tosun, David C. Greenspan, Srinivas Katta
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Publication number: 20150105748Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.Type: ApplicationFiled: December 16, 2014Publication date: April 16, 2015Applicant: NOVABONE PRODUCTS, LLCInventors: Dennis McBride, Joshua P. Clark, Richard Davis, Gregory J. Pomrink, Zehra Tosun
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Publication number: 20150079146Abstract: The invention relates to the use of a bioactive glass material. For example, an autograft chip is wrapped in bioactive glass material for the treatment of bone injuries and bone defects in the body. The material can be in one or more of several forms, such as fibers, a fiber mesh, a sheet, or another shape. The material can be applied to hard tissues, such as bone.Type: ApplicationFiled: April 5, 2013Publication date: March 19, 2015Applicant: NOVABONE PRODUCTS, LLC.Inventors: Gregory J. Pomrink, Zehra Tosun
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Publication number: 20140079789Abstract: One or more particles of bioactive glass coated with a glycosaminoglycan, wherein the glycosaminoglycan is bound to the bioactive glass and methods of treatment using such particles.Type: ApplicationFiled: September 18, 2013Publication date: March 20, 2014Applicant: NOVABONE PRODUCTS, LLCInventors: Gregory J. POMRINK, Zehra TOSUN
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Publication number: 20130330410Abstract: A composition including calcium salt and silica, wherein the silica is in the form of a silicate that is adsorbed onto the surface of the calcium salt, wherein the silica is not incorporated into the structure of the calcium salt, and wherein the composition is bioactive.Type: ApplicationFiled: June 7, 2013Publication date: December 12, 2013Applicant: NOVABONE PRODUCTS, LLCInventors: Gregory J. POMRINK, Cecilia A. CAO
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Publication number: 20110217388Abstract: This invention relates to methods for producing a composite bone graft material that can regenerate bony defects in the body. The invention further relates to methods that allow for the production of bioactive glass particles used in the composite that have been surface treated to allow for the production of a highly porous composite that can hold significant amounts of body fluid or other molecules that will aid in the regenerative process. The method of surface treatment allows for the manufacture of a suitable implantable composite while retaining the unique osteostimulative properties that are associated with bioactive glass particles.Type: ApplicationFiled: March 3, 2011Publication date: September 8, 2011Applicant: NOVABONE PRODUCTS, LLCInventors: David C. GREENSPAN, Srinivas KATTA