Patents Assigned to NOVABONE PRODUCTS, LLC
  • Patent number: 10646514
    Abstract: Methods for processing and or removing organic residuals and or impurities from a solgel-derived bioactive glass-ceramic and compositions comprising solgel-derived bioactive glass-ceramics processed using these methods, are described.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: May 12, 2020
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Chloƫ Goldbach, Gregory J. Pomrink, Roy Layne Howell, Meryem Demir
  • Patent number: 10524916
    Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 15-45% CaO, 30-70% SiO2, 0-25% Na2O, 0-17% P2O5, 0-10% MgO and 0-5% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: January 7, 2020
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Qiang Jie, Jiang Chang, Weiming J. Gu, Jipin Zhong, Gregory J. Pomrink
  • Patent number: 10143707
    Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof, which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: December 4, 2018
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. Pomrink, Jipin Zhong, Zehra Tosun, Roy Layne Howell, Cecilia Cao
  • Publication number: 20170354501
    Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 15-45% CaO, 30-70% SiO2, 0-25% Na2O, 0-17% P2O5, 0-10% MgO and 0-5% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.
    Type: Application
    Filed: June 5, 2017
    Publication date: December 14, 2017
    Applicant: NOVABONE PRODUCTS, LLC
    Inventors: Qiang Jie, Jiang Chang, Weiming J. Gu, Jipin Zhong, Gregory J. Pomrink
  • Patent number: 9707079
    Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO2, 0-25% Na2O, 5-17% P2O5, 0-5% MgO and 0-1% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: July 18, 2017
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Jiang Chang, Weiming Gu, Jipin Zhong
  • Publication number: 20170056445
    Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof, which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCI, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.
    Type: Application
    Filed: November 15, 2016
    Publication date: March 2, 2017
    Applicant: NovaBone Products, LLC
    Inventors: Gregory J. Pomrink, Jipin Zhong, Zehra Tosun, Roy Layne Howell, Cecilia Cao
  • Publication number: 20170056553
    Abstract: Compositions including bioactive glass ceramic material surface-coated with a metallic material and methods of making and using the metallic material-coated compositions.
    Type: Application
    Filed: August 30, 2016
    Publication date: March 2, 2017
    Applicant: NovaBone Products, LLC
    Inventors: Gregory J. Pomrink, Zehra Tosun, R. Layne Howell
  • Patent number: 9498459
    Abstract: A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include introducing Na2O into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 22, 2016
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. Pomrink, Jipin Zhong, Zehra Tosun, Roy Layne Howell, Cecilia Cao
  • Patent number: 9433704
    Abstract: A settable osteostimulative bone graft putty composition having a bioactive glass particulate component composed of a long-term and a short-term component; the long-term component having particle sizes greater than 90 micrometers and the short-term component having particle sizes less than 90 micrometers; the long-term component comprising about 60% to 90% of the bioactive glass osteostimulative particulate component dry weight and the short-term component comprising about 40% to 10%; a binder component having a calcium sulfate component and a calcium silicate component; the calcium sulfate component comprising about 35% to 50% of the binder component dry weight and the calcium silicate component comprising about 65% to 50%; the bioactive glass osteostimulative particulate component being about 20% to 60% of the total putty dry weight composition and the binder being about 80% to 40%; the bioactive glass particulate component and the binder component mixable in water to form the putty.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: September 6, 2016
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Jipin Zhong, David M. Gaisser
  • Publication number: 20150366908
    Abstract: A composition including calcium salt and silica, wherein the silica is in the form of a silicate that is adsorbed onto the surface of the calcium salt, wherein the silica is not incorporated into the structure of the calcium salt, and wherein the composition is bioactive.
    Type: Application
    Filed: September 1, 2015
    Publication date: December 24, 2015
    Applicant: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. Pomrink, Cecilia A. Cao
  • Patent number: 9199006
    Abstract: The present invention relates to combination products including bioactive glass and collagen as well as kits comprising the same.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: December 1, 2015
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. Pomrink, Zehra Tosun, Cecilia A. Gao, Joshua Clark, David C. Greenspan
  • Patent number: 9199032
    Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: December 1, 2015
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Dennis McBride, Joshua P. Clark, Richard Davis, Gregory J. Pomrink, Zehra Tosun, David C. Greenspan
  • Patent number: 9198936
    Abstract: This invention relates to methods for producing a composite bone graft material that can regenerate bony defects in the body. The invention further relates to methods that allow for the production of bioactive glass particles used in the composite that have been surface treated to allow for the production of a highly porous composite that can hold significant amounts of body fluid or other molecules that will aid in the regenerative process. The method of surface treatment allows for the manufacture of a suitable implantable composite while retaining the unique osteostimulative properties that are associated with bioactive glass particles.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: December 1, 2015
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: David C. Greenspan, Srinivas Katta
  • Patent number: 9144629
    Abstract: Compositions including crosslinked collagen and bioactive glass having an average pore size of at least 100 microns and methods of preparation thereof.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 29, 2015
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. Pomrink, Cecilia A. Cao, Joshua Clark, Zehra Tosun, David C. Greenspan, Srinivas Katta
  • Publication number: 20150105748
    Abstract: Methods for producing a composite bone graft material that can regenerate bony defects in the body are provided. Also, methods, kits and delivery systems for a minimally invasive delivery of a composition for regenerating bone at or near the site of a bony defect that include, the composition for regenerating bone comprising collagen and bioactive glass are provided.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 16, 2015
    Applicant: NOVABONE PRODUCTS, LLC
    Inventors: Dennis McBride, Joshua P. Clark, Richard Davis, Gregory J. Pomrink, Zehra Tosun
  • Publication number: 20150079146
    Abstract: The invention relates to the use of a bioactive glass material. For example, an autograft chip is wrapped in bioactive glass material for the treatment of bone injuries and bone defects in the body. The material can be in one or more of several forms, such as fibers, a fiber mesh, a sheet, or another shape. The material can be applied to hard tissues, such as bone.
    Type: Application
    Filed: April 5, 2013
    Publication date: March 19, 2015
    Applicant: NOVABONE PRODUCTS, LLC.
    Inventors: Gregory J. Pomrink, Zehra Tosun
  • Publication number: 20140231291
    Abstract: The present invention relates to combination products including bioactive glass and collagen as well as kits comprising the same.
    Type: Application
    Filed: March 27, 2014
    Publication date: August 21, 2014
    Applicant: NovaBone Products, LLC
    Inventors: Gregory J. Pomrink, Zehra Tosun, Cecilia A. Cao, Joshua Clark
  • Patent number: 8795702
    Abstract: This invention relates to methods for producing a composite bone graft material that can regenerate bony defects in the body. The invention further relates to methods that allow for the production of bioactive glass particles used in the composite that have been surface treated to allow for the production of a highly porous composite that can hold significant amounts of body fluid or other molecules that will aid in the regenerative process. The method of surface treatment allows for the manufacture of a suitable implantable composite while retaining the unique osteostimulative properties that are associated with bioactive glass particles.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: August 5, 2014
    Assignee: Novabone Products, LLC
    Inventors: David C. Greenspan, Srinivas Katta
  • Publication number: 20140079789
    Abstract: One or more particles of bioactive glass coated with a glycosaminoglycan, wherein the glycosaminoglycan is bound to the bioactive glass and methods of treatment using such particles.
    Type: Application
    Filed: September 18, 2013
    Publication date: March 20, 2014
    Applicant: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. POMRINK, Zehra TOSUN
  • Publication number: 20130330410
    Abstract: A composition including calcium salt and silica, wherein the silica is in the form of a silicate that is adsorbed onto the surface of the calcium salt, wherein the silica is not incorporated into the structure of the calcium salt, and wherein the composition is bioactive.
    Type: Application
    Filed: June 7, 2013
    Publication date: December 12, 2013
    Applicant: NOVABONE PRODUCTS, LLC
    Inventors: Gregory J. POMRINK, Cecilia A. CAO