Patents Assigned to Novacardia, Inc.
  • Method of improved diuresis in individuals with impaired renal function
    Patent number: 7579331
    Abstract: Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: August 25, 2009
    Assignee: Novacardia, Inc.
    Inventors: Kenneth J. Widder, Lauren Otsuki, Howard C. Dittrich, Scott Thomson, Roland Blantz