Patents Assigned to NovaDigm Therapeutics, Inc.
  • Methods and kits for use in preventing and treating vulvovaginal candidiasis
    Patent number: 10857216
    Abstract: The invention features methods and kits use in for preventing and treating vulvovaginal candidiasis (VVC), in particular, recurrent VVC.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: December 8, 2020
    Assignees: NovaDigm Therapeutics, Inc., Los Angeles Biomedical Institute at Harbor-UCLA Medical Center
    Inventors: John E. Edwards, Jr., Scott G. Filler, John P. Hennessey, Jr., Michael Timothy Cooke, Jack D. Sobel
  • Methods and compositions for vaccinating against
    Patent number: 10653757
    Abstract: The invention features a method of vaccinating a mammal against Staphylococcus aureus which includes the steps of: a) identifying a mammal at risk for the development of a Staphylococcus aureus skin or soft tissue infection; and b) administering to said mammal an immunogenic amount of a vaccine that includes a polypeptide including an isolated agglutinin-like sequence (Als) 3 protein (Als3p), or an immunogenic fragment thereof, in a pharmaceutically acceptable medium.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: May 19, 2020
    Assignees: NovaDigm Therapeutics, Inc., Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, John E. Edwards, Jr., Scott G. Filler, Ashraf S. Ibrahim, Yue Fu, John P. Hennessey, Jr.
  • Compositions and methods for treating fungal and bacterial pathogens
    Patent number: 10130691
    Abstract: The invention features fragments of the Candida cell surface proteins Als3 and Hyr1 and combinations thereof useful in immunizing a subject against fungal or bacterial infections or both.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 20, 2018
    Assignees: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, NovaDigm Therapeutics, Inc.
    Inventors: Ashraf S. Ibrahim, Michael R. Yeaman, Scott G. Filler, John E. Edwards, Jr., John P. Hennessey, Jr.
  • Truncated secretory aspartyl proteinase 2
    Patent number: 9610334
    Abstract: The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: April 4, 2017
    Assignees: Istituto Superiore di Sanita, NovaDigm Therapeutics, Inc.
    Inventors: Rinaldo Zurbriggen, Flavia De Bernardis, Antonio Cassone, Silvia Rasi
  • COMPOSITIONS AND METHODS FOR TREATING FUNGAL AND BACTERIAL PATHOGENS
    Publication number: 20160030534
    Abstract: The invention features fragments of the Candida cell surface proteins Als3 and Hyr1 and combinations thereof useful in immunizing a subject against fungal or bacterial infections or both.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicants: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, NovaDigm Therapeutics, Inc.
    Inventors: Ashraf S. IBRAHIM, Michael R. YEAMAN, Scott G. FILLER, John E. EDWARDS, JR., John P. HENNESSEY, JR.
  • METHODS AND COMPOSITIONS FOR VACCINATING AGAINST STAPHYLOCOCCUS AUREUS
    Publication number: 20150273031
    Abstract: The invention features a method of vaccinating a mammal against Staphylococcus aureus which includes the steps of: a) identifying a mammal at risk for the development of a Staphylococcus aureus skin or soft tissue infection; and b) administering to said mammal an immunogenic amount of a vaccine that includes a polypeptide including an isolated agglutinin-like sequence (Als) 3 protein (Als3p), or an immunogenic fragment thereof, in a pharmaceutically acceptable medium.
    Type: Application
    Filed: July 20, 2012
    Publication date: October 1, 2015
    Applicants: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, NovaDigm Therapeutics, Inc.
    Inventors: Michael R. Yeaman, John E. Edwards, JR., Scott G. Filler, Ashraf S. Ibrahim, Yue Fu, John P. Hennessey, JR.