Patents Assigned to NOVADIP BIOSCIENCES
  • CELLULAR AND/OR EXTRACELLULAR EXTRACTS FOR PREVENTING AND/OR TREATING CANCER AND/OR INFLAMMATION
    Publication number: 20240000848
    Abstract: The present invention relates to a pharmaceutical composition for use in the prevention and/or the treatment of cancer and/or inflammation, comprising (i) a cellular and/or extracellular extract(s) obtained from a scaffold-free 3-dimensional culture of mature cells and a particulate material, wherein the mature cells secreted an extracellular matrix, and wherein the mature cells and the particulate material were embedded in the extracellular matrix; and (ii) a pharmaceutically acceptable excipient.
    Type: Application
    Filed: November 26, 2021
    Publication date: January 4, 2024
    Applicant: NOVADIP BIOSCIENCES
    Inventor: DENIS DUFRANE
  • Biomaterial comprising adipose-derived stem cells and method for producing the same
    Patent number: 11602579
    Abstract: The present invention relates to a biomaterial comprising adipose-derived stem cells (ASCs), a ceramic material and an extracellular matrix. In particular, the biomaterial according the present invention secretes osteoprotegerin (OPG), and comprises insulin-like growth factor (IGF1) and stromal cell-derived factor 1-alpha (SDF-1?). The present invention also relates to methods for producing the biomaterial and uses thereof.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: March 14, 2023
    Assignee: NOVADIP BIOSCIENCES
    Inventor: Denis Dufrane
  • miRNA-BASED PHARMACEUTICAL COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND THE TREATMENT OF TISSUE DISORDERS
    Publication number: 20220409652
    Abstract: The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of (i) at least three miRNAs selected in any one of Table 1, Table 2, Table 3, Table 4, Table 5, Table 6, Table 7, Table 8, Table 9, Table 10, Table 11 or Table 12 and (ii) a pharmaceutical acceptable vehicle. The pharmaceutical composition according to the invention may be of therapeutic use for the prevention and/or the treatment of tissue disorders, including, but not limited to skin disorders, bone disorders and/or cartilage disorders.
    Type: Application
    Filed: November 27, 2020
    Publication date: December 29, 2022
    Applicant: NOVADIP BIOSCIENCES
    Inventor: DENIS DUFRANE
  • Methods for assessing the purity of a mesenchymal stem cells preparation
    Patent number: 11203785
    Abstract: The present invention relates to a method for assessing, evaluating and/monitoring the purity of a mesenchymal stem cells preparation, in particular of an adipose stem cells preparation, comprising measuring the expression level of at least one growth factor.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: December 21, 2021
    Assignees: UNIVERSITÉ CATHOLIQUE DE LOUVAIN, CLINIQUES UNIVERSITAIRES SAINT-LUC, NOVADIP BIOSCIENCES SA
    Inventor: Denis Dufrane
  • METHODS FOR ASSESSING THE PURITY OF A MESENCHYMAL STEM CELLS PREPARATION
    Publication number: 20180135124
    Abstract: The present invention relates to a method for assessing, evaluating and/monitoring the purity of a mesenchymal stem cells preparation, in particular of an adipose stem cells preparation, comprising measuring the expression level of at least one growth factor.
    Type: Application
    Filed: May 9, 2016
    Publication date: May 17, 2018
    Applicants: UNIVERSITÉ CATHOLIQUE DE LOUVAIN, CLINIQUES UNIVERSITAIRES SAINT-LUC, NOVADIP BIOSCIENCES SA
    Inventor: Denis DUFRANE