Abstract: Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vaccines containing same, methods for production of same and methods for use of same.
Type:
Grant
Filed:
December 20, 1984
Date of Patent:
September 2, 1986
Assignees:
Novagene, Ltd., Baylor College of Medicine
Abstract: Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for administering them to animals in immunologically effective doses to induce resistance to infectious bovine rhinotracheitis.
Type:
Grant
Filed:
July 21, 1983
Date of Patent:
February 11, 1986
Assignees:
Baylor College of Medicine, NovaGene, Ltd.
Abstract: Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of a deletion in the tk gene, vaccines containing same, methods for production of same and methods for use of same.
Type:
Grant
Filed:
December 30, 1983
Date of Patent:
April 30, 1985
Assignees:
Novagene, Ltd., Baylor College of Medicine