Abstract: The present invention relates to methods for recellularization of blood vessels. This method is particularly useful for producing an allogeneic vein, wherein a donor vein is decellularized and then recellularized using whole blood or bone marrow stem cells. The allogeneic veins produced by the methods disclosed herein are particularly advantageous for implantation or transplantation into patients with vascular diseases.
March 1, 2013
Date of Patent:
July 28, 2015
Suchitra Sumitran-Holgersson, Michael Olausson