Patents Assigned to Novalar Pharmaceuticals, Inc.
  • Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof
    Patent number: 7575757
    Abstract: The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: August 18, 2009
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Andrew X. Chen, Julius Knowles, Eckard Weber
  • Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof
    Patent number: 7569230
    Abstract: The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: August 4, 2009
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Andrew X Chen, Julius Knowles, Eckard Weber
  • Local Anesthetic Methods and Kits
    Publication number: 20090076023
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Application
    Filed: November 21, 2008
    Publication date: March 19, 2009
    Applicant: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard WEBER, Howard I. Katz
  • Characterization of an antibiotic impregnated delivery system as an intracanal medicament in endodontic therapy
    Patent number: 7331787
    Abstract: Endodontic fibers comprising a biocompatible polymer vehicle permeable to medicaments, or combinations of medicaments are described. Such fibers can be used, for example, in a method for the local delivery and sustained release of medicaments to periodontal or intracanal treatment sites. Endodontic fibers described include modified periodontal fibers and intracanal fibers.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: February 19, 2008
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Mario Abdennour, Philip Stashenko, Michele Scrime, Jack Gilad, Max Goodson
  • Local anesthetic methods and kits
    Patent number: 7261889
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: August 28, 2007
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Stabilized formulations of alpha adrenergic receptor antagonists and the uses thereof
    Patent number: 7229630
    Abstract: The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: June 12, 2007
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Andrew X. Chen, Julius Knowles, Eckard Weber
  • Local anesthetic methods and kits
    Patent number: 6872390
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: March 29, 2005
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Local anesthetic methods and kits
    Publication number: 20040198816
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Application
    Filed: April 5, 2004
    Publication date: October 7, 2004
    Applicant: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Local anesthetic methods and kits
    Patent number: 6764678
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: July 20, 2004
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Local anesthetic methods and kits
    Publication number: 20020183396
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 5, 2002
    Applicant: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Local anesthetic methods and kits
    Publication number: 20020183356
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Application
    Filed: May 28, 2002
    Publication date: December 5, 2002
    Applicant: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I Katz
  • Local anesthetic methods and kits
    Patent number: 6432401
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: August 13, 2002
    Assignee: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz
  • Local anesthetic methods and kits
    Publication number: 20010056125
    Abstract: Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.
    Type: Application
    Filed: May 11, 2001
    Publication date: December 27, 2001
    Applicant: Novalar Pharmaceuticals, Inc.
    Inventors: Eckard Weber, Howard I. Katz