Abstract: New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Type:
Application
Filed:
July 24, 2012
Publication date:
November 15, 2012
Applicant:
Novartis Vaccines and Diagnostics, Inc. formerly known as Chiron Corporation
Inventors:
Payman Amiri, Wendy Fantl, Barry Haskell Levine, Daniel J. Poon, Savithri Ramurthy, Paul A. Renhowe, Sharadha Subramanian, Leonard Sung