Patents Assigned to NOVARTIS VACCINES INSTITUTE FOR GLOBAL HEALTH SRL
  • PURIFICATION OF BACTERIAL VESICLES
    Publication number: 20130017219
    Abstract: A two stage size filtration process is used to purify immunogenic bacterial vesicles. A first step separates the vesicles from intact bacteria based on their different sizes, with the smaller vesicles passing into the filtrate (permeate). A second step then uses a finer filter to remove smaller contaminants, with the vesicles remaining in the retentate. This two stage process is extremely simple to operate but has been shown to give vesicles of high purity.
    Type: Application
    Filed: September 28, 2010
    Publication date: January 17, 2013
    Applicant: NOVARTIS VACCINES INSTITUTE FOR GLOBAL HEALTH SRL
    Inventors: Vito Di Cioccio, Anna Maria Colucci, Allan James Saul