Patents Assigned to NOVARTIS VACCINESS AND DIAGNOSTICS
  • HYBRID AND TANDEM EXPRESSION OF NEISSERIAL PROTEINS
    Publication number: 20110250223
    Abstract: Two or more Neisserial proteins are joined such that they are translated as a single polypeptide chain. Hybrid proteins are represented by the formula NH2-A-[-X-L-]n-B—COOH where X is an amino acid sequence, L is an optional linker amino acid sequence, A is an optional N-terminal amino acid sequence, B is an optional C-terminal amino acid sequence, and n is an integer greater than I. Proteins where each of the n —X— moieties shares sequence identity to each other —X— moiety, the protein is a ‘tandem protein’.
    Type: Application
    Filed: June 13, 2011
    Publication date: October 13, 2011
    Applicant: NOVARTIS VACCINESS AND DIAGNOSTICS
    Inventor: Mariagrazia PIZZA