Patents Assigned to NOVARTS AG
  • IL-17 antibodies
    Patent number: 8617552
    Abstract: An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to human IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-17 mediated disease or disorder, e.g. rheumatoid arthritis.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: December 31, 2013
    Assignee: Novarts AG
    Inventors: Franco E Di Padova, Hermann Gram, Hans Hofstetter, Margit Jeschke, Jean-Michel Rondeau, Wim Van Den Berg
  • Effects of Inhibitors of Fgfr3 on Gene Transcription
    Publication number: 20090048266
    Abstract: Methods of utilizing biomarkers to identify patients for treatment or to monitor response to treatment are taught herein. Alterations in levels of gene expression of the biomarkers, particularly in response to FGFR3 inhibition, are measured and identifications or adjustments may be made accordingly.
    Type: Application
    Filed: December 7, 2006
    Publication date: February 19, 2009
    Applicant: NOVARTS AG
    Inventors: Carla Heise, Esther Masih-Khan, Edward Moler, Michael Rowe, Keith Stewart, Suzanne Trudel