Abstract: A drive mechanism for operating a suturing mechanism includes a user input displaceable through a range of motion and a linkage mechanically associated with the user input and with a shuttle transmitter of the suturing mechanism. The linkage converts displacements of the user input unidirectionally or bidirectionally into a sequence of operations of the shuttle transmitter including sufficient to perform a sequence of operations of the suturing mechanism to perform successive bidirectional stitching, with the shuttle transmitter penetrating tissue alternately with and without a shuttle needle attached.

Abstract: A suturing device includes a shuttle for holding a suture, a shuttle transmitter and a shuttle receiver. The shuttle transmitter includes a shuttle holder for holding the shuttle and a shuttle releaser displaceable relative to the shuttle holder for releasing the shuttle from the shuttle holder. The shuttle holder advances through a material at a first location while holding the shuttle until the shuttle engages the shuttle receiver. The shuttle releaser then releases the shuttle from the shuttle holder for withdrawal of the shuttle transmitter through the material, leaving the shuttle engaged with the shuttle receiver. The shuttle transmitter the penetrates the material at a second location opposite the shuttle receiver and retrieves the shuttle, holding it while withdrawing through the material at the second location. This sequence can be repeated to form a wide range of multi-stitch suture patterns for vascular closure and a wide range of other applications.