Abstract: The invention relates to a method for forgery-proof labeling of items, such as credit cards, bank notes and the like, comprising the following steps: (a) applying, to a first layer (1) that reflects electromagnetic waves, an inert second layer (3) that is permeable to electromagnetic waves, said second layer having a predetermined thickness, (b) applying, to said second layer (3), a third layer (4) that is formed by metal clusters, and (c) linking the first layer (1) of the label so produced with the item.

Abstract: The invention relates to forgery-proof marking for objects, such as check cards, banknotes, labels, and the like, comprising a plastic transparent film (1) having a first and second surface, whereby a series of layers is applied to the second surface. When viewed from the first surface, the color of this series of layers changes according to the viewing angle, and the series of layers is formed from an absorber layer provided on the second surface, from a spacer layer (3) overlying the absorber layer, and from a mirror layer (2) overlying the spacer layer (3). In order to improve the machine identification of the authenticity of the marking, the invention provides that the absorber layer is comprised of metallic clusters (4).

Abstract: The invention relates to a method for indirectly determining the blood-clotting status.

Abstract: A device for the electrochemical detection of at least one biochemical molecule contained in a liquid from a group of predetermined biochemical molecules includes a holder (1) for taking up the liquid, with at least one reference electrode (RE) and at least one counterelectrode (GE) and a multiplicity of working electrodes (AE1, AE2, AE3). At least one working electrode is provided for the detection of each biochemical molecule, and is coated with a molecule that is complementary to the respective biochemical molecule, so that the biochemical molecules can be detected simultaneously. The device includes a potentiostat (P) for generating a predetermined voltage profile between the working electrodes and the reference electrode, a current/voltage converter (S1, S2, S3) connected downstream of each of the working electrodes for holding all of the working electrodes at the same potential, and a measurement device (Ad) for measuring the currents flowing through the working electrodes.

Abstract: The invention relates to a method for identifying a first polymer (4, 7) which is bonded to a first phase (5) that reflects electromagnetic waves. Said method comprises the following steps: (a) bringing the first polymer (4, 7) into contact with a second polymer (3, 8), which is bonded to a solid second phase (1) by metallic clusters (2), said second phase being permeable to electromagnetic waves; (b) irradiating the second phase (1) with electromagnetic waves; and (c) determining the change in the properties of the reflected electromagnetic waves.

Abstract: The invention relates to a synthetic, biologically active molecule for fixing an active ingredient to the virus protein 1 (VP1) of the polyoma virus. According to the invention, an amino acid sequence A1 which is derived from the C-terminal end of virus protein 2 (VP2) or 3 (VP3) of the polyoma virus is bonded to an active ingredient at one of its ends.

Abstract: The invention relates to a device for checking the authenticity of an anti-forgery marking with colours which change depending on the angle of observation, comprising a) several first light sources, emitting in a given spectral range, whereby the light sources are different from each other with regard to the wavelength of the emission maximum thereof and the first light sources (1) are housed in a housing (5) such as to irradiate the surface (O), with the housing (5) placed thereon, at a given first angle (?1), b) a first means (2) for measuring the intensity of the light reflected from the surface (O) arranged at a second angle (?2) and c) a means (7) for the automatic comparison of measured intensities with the reference intensities stored for at least one given colour for each light source (1).

Abstract: The invention relates to a device for conducting biochemical and microbiological reactions, comprising a support (2) for receiving at least one reaction vessel (3) and a device (5) for pressing a closing means (11, 12) sealing the reaction vessel (3), wherein the closing means (11, 12) project in closed position in the area surrounded by the reaction vessel (3). According to the invention, in order to accelerate and simplify reaction, an inner wall of the closing means opposite the reaction vessel (3) is coated with a molecule (14) on which a molecule to be detected can be bonded or deposited, wherein the molecule (14) contains a nucleic acid, an amino acid or a synthetic derivative of a nucleic or amino acid.

Abstract: A method for perforating skin including a lancet (1) held in a lancet holder (2) which, by means of a spring-loaded element (9), can be locked in a housing and moved out of the housing. To improve hygiene the invention provides for the lancet holder to be housed in a cup (5), which can be attached to the housing (8), and slidably guided in the cup.

Abstract: The invention relates to an agent for detecting chemical substances, comprising: a first polynucleotide or peptide sequence having a first fluorophore molecule, the first end of said sequence being bonded on a solid phase and a second polynucleotide or peptide sequence having a second fluorophore molecule, the second end of said sequence having a group that is sensitive to the chemical substance to be detected. The first polynucleotide or peptide sequence can be hybridized to the second polynucleotide or peptide sequence in such a way that a spatial relationship enabling an interaction betweeen the first and the second fluorophore molecule is produced. When the chemical substance including a physical property is attached to the group and the influence of an external force is exerted on the physical property, the spatial relation can be eliminated, thereby generating or abolishing a fluorescent reaction.

Abstract: The invention relates to a process for recombinantly preparing picornavirus particles, in particular hepatitis A virus particles, their precursors and particles which are derived therefrom, with a structural protein precursor molecule (P1-2A or P1) and the corresponding P3 region (3ABCD) being coexpressed in cis or in trans.

Abstract: A method for preparing samples for detecting a nucleotide sequence by polymerase chain reaction (PCR) according to which a) an analysis solution is filled into at least one cavity (2) provided for in a support (1); b) a lid (3) configured complementary to the shape of the cavity (2) is placed onto the support (1) in such a way that the analysis solution is pushed at least partly into a gap (S) formed between the cavity (2) and the lid (3); and c) the gap (S) is sealed by means of at least one seal (5, 12) provided for near an opening in the cavity (2).

Abstract: The invention relates to a method for preparing samples for detecting a nucleotide sequence by polymerase chain reaction (PCR), according to which a) an analysis solution is filled into at least one cavity (2) provided for in a support (1); b) a lid (3) configured complementary to the shape of the cavity (2) is placed onto the support (1) in such a way that the analysis solution is pushed at least partly into a gap (S) formed between the cavity (2) and the lid (3); and c) the gap (S) is sealed by means of at least one seal (5, 12) provided for near an opening in the cavity (2).

Abstract: The invention relates to a device for the contamination-free delivery and discharge of liquid into and from a reaction vessel 15, having a tube 1, one end of which [lacuna] designed as a first connection fitting 2 for connection to a pipette or the like and the other end of which has a first opening 3. In order to avoid contamination when the reaction vessel is filled with and drained of liquids, it is proposed that a second connection fitting 4, which is in communication with at least a second opening 8, is provided in the vicinity of the first end.

Abstract: The invention refers to a cap for containers for holding a mixture to be produced from two components, having a cylinder (5) with an open end and an end closed by a partition (6) which can be perforated, a piston (1) having a gripping piece (2) of larger design than the cylinder diameter being inserted into the open end of the cylinder, such that a first chamber (K1) having a height (h) is formed between a lower side (KU) of the piston lying opposite the gripping piece (2) and the partition (6), characterized in that two incisions (7) extending from the open end of the cylinder and lying opposite each other are provided in the cylinder wall, and in that the gripping piece (2) is designed in such a manner that it can be displaced in the incisions (7) in order to move the piston (1) in the direction of the partition (6).

Abstract: The invention relates to a method of detecting and identifying nucleic aicd (NA) molecules within a population (I) of NA molecules of identical, similar or different sequence, in which: (a) the single-stranded or duplex ribonucleic acid (RNA) molecules or single-stranded deoxyribonucleic aicd (DNA) molecules contained in a population (I) iare convereted into a population (II) of duplex DNA molecules; b) the population (II) of duplex DNA molecules is subjected to denaturation and subsequent renaturation, so that a mixture of homo- and heteroduplex DNA molecules is present; c) heteroduplexes formed in the population (II) where unpaired of incorrectly paired nucleotides are present are reacted chemically with a carbodiimide compound; and d) the resulting carboddimide reactions products are characterized and quantified, characterized in that a chromatographic purification method is carried out between each of the steps a to d.

Abstract: The invention relates to a method for marking solid, liquid or gaseous substances, whereby the substance to be marked is provided with at least one synthetically produced nucleic acid sequence. Said nucleic acid sequence contains a first sequence section constructed with the 5′ terminal end, a second sequence comprised of at least two bases and connected to said nucleic acid sequence, and a third sequence section constructed with the 3′ terminal end and connected to the said nucleic acid sequence. In order to simplify the identification of the marking, the invention provides that a first primer group is used with a first primer section corresponding to the first sequence section and a second primer group is used with a third primer section corresponding to the third sequence section.