Abstract: The present invention provides preparations of Factor VIIa polypeptides or Factor VIIa-related polypeptides that exhibit predetermined glycoform patterns. The preparations of the invention exhibit improved functional properties and are useful for treating Factor VII-mediated conditions.
Type:
Grant
Filed:
October 2, 2001
Date of Patent:
June 7, 2005
Assignee:
Novo Nordisk Health Care A/S
Inventors:
Hans Kurt Pingel, Niels Kristian Klausen