Patents Assigned to Novozymes, Inc.
  • Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Patent number: 9562248
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: February 7, 2017
    Assignee: NOVOZYMES INC.
    Inventors: Ye Liu, Lan Tang, Junxin Duan
  • Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
    Patent number: 9562222
    Abstract: The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: February 7, 2017
    Assignees: NOVOZYMES A/S, NOVOZYMES, INC.
    Inventor: Marc Morant
  • HYBRID POLYPEPTIDES HAVING CELLOBIOHYDROLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20170022489
    Abstract: The present invention relates to hybrid polypeptides having cellobiohydrolase activity. The present invention also relates to polynucleotides encoding the hybrid polypeptides; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and processes of using the hybrid polypeptides.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Applicant: NOVOZYMES, INC.
    Inventors: Ye Liu, Tarana Shaghasi
  • Lipase variants for pharmaceutical use
    Patent number: 9539311
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, an are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: January 10, 2017
    Assignees: Novozymes A/S, Novozymes Inc.
    Inventors: Allan Svendsen, Michael Skjoet, Debbie Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Polypeptides having xylanase activity and polynucleotides encoding same
    Patent number: 9534211
    Abstract: The present invention relates to isolated polypeptides having xylanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: January 3, 2017
    Assignees: NOVOZYMES A/S, NOVOZYMES, INC.
    Inventors: Elena Vlasenko, Brett McBrayer, Dominique Skovlund, Sara Landvik
  • POLYPEPTIDES HAVING CELLOBIOHYDROLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20160369252
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 22, 2016
    Applicant: NOVOZYMES, INC.
    Inventors: Marc D. Morant, Paul Harris
  • Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Patent number: 9518253
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: December 13, 2016
    Assignee: NOVOZYMES, INC.
    Inventor: Nikolaj Spodsberg
  • Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
    Patent number: 9506046
    Abstract: The present invention relates to isolated polypeptides having amylolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: November 29, 2016
    Assignee: Novozymes, Inc.
    Inventors: Paul Harris, Mark Wogulis
  • Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Patent number: 9506048
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity, catalytic domains, and cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains, and cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, or cellulose binding domains.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: November 29, 2016
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Mary Ann Stringer, Brett McBrayer
  • Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
    Patent number: 9506049
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: November 29, 2016
    Assignees: Novozymes A/S, Novozymes, Inc.
    Inventors: Lan Tang, Ye Liu, Junxin Duan, Yu Zhang, Christian Joergensen, Randall Kramer
  • Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
    Patent number: 9499806
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: November 22, 2016
    Assignee: Novozymes, Inc.
    Inventors: Yu Zhang, Junxin Duan, Lan Tang, Wenping Wu
  • Methods of eliminating or reducing expression of genes in filamentous fungal strains by transitive RNA interference
    Patent number: 9499820
    Abstract: The present invention relates to methods of reducing or eliminating expression of a target gene in a filamentous fungal strain by transitive RNA interference.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: November 22, 2016
    Assignee: NOVOZYMES, INC.
    Inventors: Howard Brody, Donna Moyer, Amanda Fisher
  • Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
    Patent number: 9493759
    Abstract: The present invention relates to isolated polypeptides having aspartic endopeptidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: November 15, 2016
    Assignee: Novozymes, Inc.
    Inventors: Beth Nelson, Alfredo Lopez de Leon, Michael Rey
  • Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
    Patent number: 9493790
    Abstract: The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: November 15, 2016
    Assignee: Novozymes, Inc.
    Inventors: Debbie Yaver, Qiming Jin
  • Hybrid polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Patent number: 9481897
    Abstract: The present invention provides hybrid polypeptides having cellobiohydrolase activity. The present invention also provides polynucleotides encoding the hybrid polypeptides; nucleic acid constructs, vectors and host cells comprising the polynucleotides; and processes of using the hybrid polypeptides.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 1, 2016
    Assignee: NOVOZYMES, INC.
    Inventors: Ye Liu, Tarana Shaghasi
  • Cellulolytic enzyme compositions and uses thereof
    Patent number: 9476036
    Abstract: The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: October 25, 2016
    Assignee: Novozymes, Inc.
    Inventors: Jeffrey Shasky, Amanda Fischer, Suchindra Maiyuran
  • Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof
    Patent number: 9458483
    Abstract: The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a bicyclic compound. The present invention also relates to methods of using the compositions.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: October 4, 2016
    Assignee: NOVOZYMES, Inc.
    Inventors: Jason Quinlan, Feng Xu, Matthew Sweeney
  • Methods of increasing the cellulolytic enhancing activity of a polypeptide
    Patent number: 9453213
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: September 27, 2016
    Assignee: Novozymes, Inc.
    Inventors: Keith McFarland, Paul Harris
  • Microorganisms for C4-dicarboxylic acid production
    Patent number: 9447440
    Abstract: The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: September 20, 2016
    Assignee: Novozymes, Inc.
    Inventors: Amanda Fischer, Stephen Brown, Sheryl Luttringer
  • Polypeptides having endoglucanase activity and polynucleotides encoding same
    Patent number: 9428742
    Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: August 30, 2016
    Assignees: NOVOZYMES, INC., NOVOZYMES A/S
    Inventors: Soren Flensted Lassen, Paul Harris, Elena Vlasenko, Kristian Krogh