Patents Assigned to Novozymes, Inc.
  • Patent number: 10900047
    Abstract: The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: January 26, 2021
    Assignee: Novozymes Inc.
    Inventors: Yu Zhang, Ye Liu, Junxin Duan, Lan Tang, Brett McBrayer
  • Patent number: 10889844
    Abstract: The invention provides a method of degrading or hydrolyzing a polysaccharide, preferably cellulose or chitin, comprising contacting said polysaccharide with one or more oxidohydrolytic enzymes, preferably a CBM33 family protein (preferably CBP21) or a GH61 family protein, wherein said degradation or hydrolysis is carried out in the presence of at least one reducing agent and at least one divalent metal ion. A method of producing an organic substance comprising said method is also provided.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: January 12, 2021
    Assignees: Novozymes A/S, Novozymes, Inc.
    Inventors: Gustav Vaaje-Kostad, Bjorge Westereng, Vincent G. H. Eijsink, Svein J. Horn, Morten Sorliie, Zarah Forsberg
  • Patent number: 10883129
    Abstract: The present invention relates to enzyme compositions comprising a polypeptide having cellobiohydrolase II activity, a polypeptide having xylanase activity, and one or more cellulolytic proteins and their use in the degradation or conversion of cellulosic material.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: January 5, 2021
    Assignee: Novozymes, Inc.
    Inventors: Kimberly Brown, Eric Abbate
  • Publication number: 20200385773
    Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 10, 2020
    Applicant: Novozymes, Inc.
    Inventors: Suchindra Maiyuran, Abigail Jang, Kimberly Brown, Sandra Merino, Jeffrey Shasky, Eric Abbate
  • Publication number: 20200385772
    Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 10, 2020
    Applicant: Novozymes, Inc.
    Inventors: Suchindra Maiyuran, Abigail Jang, Kimberly Brown, Sandra Merino, Jeffrey Shasky, Eric Abbate
  • Publication number: 20200377921
    Abstract: The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes selected from the group consisting of a first subtilisin-like serine protease gene, a first aspartic protease gene, a trypsin-like serine protease gene, a second subtilisin-like serine protease gene, and a second aspartic protease gene, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of a first subtilisin-like serine protease, a first aspartic protease, a trypsin-like serine protease, a second subtilisin-like serine protease, and a second aspartic protease, respectively, compared to the parent Trichoderma strain when cultivated under identical conditions. The present invention also relates to methods of producing a polypeptide in such mutants and methods for producing such mutants.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicant: Novozymes, Inc.
    Inventors: Suchindra Maiyuran, Abigail Jang, Kimberly Brown, Sandra Merino, Jeffrey Shasky, Eric Abbate
  • Patent number: 10822601
    Abstract: The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: November 3, 2020
    Assignee: Novozymes, Inc.
    Inventors: Debbie Yaver, Qiming Jin
  • Patent number: 10815468
    Abstract: The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: October 27, 2020
    Assignee: Novozymes, Inc.
    Inventors: Nikolaj Spodsberg, Tarana Shaghasi
  • Patent number: 10793845
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: October 6, 2020
    Assignees: Novozymes A/S, Novozymes, Inc.
    Inventors: Nikolaj Spodsberg, Tarana Shaghasi, Matt Sweeney, Feng Xu, Kirk Schnorr
  • Patent number: 10704034
    Abstract: The present invention provides isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: July 7, 2020
    Assignee: Novozymes Inc.
    Inventors: Lan Tang, Ye Liu, Yu Zhang, Junxin Duan
  • Patent number: 10689636
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: June 23, 2020
    Assignee: Novozymes, Inc.
    Inventors: Keith McFarland, Paul Harris
  • Publication number: 20200157517
    Abstract: The present invention relates to methods for degrading or converting a cellulosic material, comprising: treating the cellulosic material with an enzyme composition in the presence of a polypeptide having cellulolytic enhancing activity.
    Type: Application
    Filed: January 28, 2020
    Publication date: May 21, 2020
    Applicant: Novozymes, Inc.
    Inventors: Ashley Garner, Paul Vincent Harris, Jason Quinlan, Randall Kramer
  • Publication number: 20200157556
    Abstract: The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: January 24, 2020
    Publication date: May 21, 2020
    Applicant: Novozymes Inc.
    Inventors: Yu Zhang, Ye Liu, Junxin Duan, Lan Tang, Brett McBrayer
  • Publication number: 20200148730
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: December 17, 2019
    Publication date: May 14, 2020
    Applicant: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Patent number: 10647972
    Abstract: The present invention relates to methods for obtaining positive transformants of a filamentous fungal host cell, comprising: transforming a tandem construct into a population of cells of the filamentous fungal host a tandem construct and isolating a transformant of the filamentous fungal host cell comprising the tandem construct. The present invention also relates to such tandem constructs, filamentous fungal host cells comprising such tandem constructs, and methods of producing multiple recombinant proteins.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: May 12, 2020
    Assignee: Novozymes, Inc.
    Inventor: Donna Moyer
  • Patent number: 10626385
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity, catalytic domains, and cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains, and cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, or cellulose binding domains.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: April 21, 2020
    Assignees: NOVOZYMES A/S, NOVOZYMES, INC.
    Inventors: Mary Ann Stringer, Brett McBrayer
  • Patent number: 10626386
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: April 21, 2020
    Assignee: Novozymes, Inc.
    Inventors: Suchindra Maiyuran, Randall Kramer, Paul Harris
  • Publication number: 20200087645
    Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.
    Type: Application
    Filed: July 22, 2016
    Publication date: March 19, 2020
    Applicant: Novozymes, Inc.
    Inventors: Paul Vincent Harris, Martin Simon Borchert, Sumati Hasani, Fang Liu
  • Patent number: 10577594
    Abstract: The present invention relates to isolated polypeptides having arabinofuranosidase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: March 3, 2020
    Assignee: Novozymes, Inc.
    Inventors: Paul Vincent Harris, Sumati Hasani, Fang Liu
  • Patent number: 10577622
    Abstract: The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: March 3, 2020
    Assignee: Novozymes Inc.
    Inventors: Yu Zhang, Ye Liu, Junxin Duan, Lan Tang, Brett McBrayer