Patents Assigned to Novozymes
  • Publication number: 20110104759
    Abstract: The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and an alpha-amylase amino acid sequence as well as to the application of such polypeptides.
    Type: Application
    Filed: December 20, 2010
    Publication date: May 5, 2011
    Applicants: Novozymes A/S, Novozymes North America, Inc.
    Inventors: Shiro Fukuyama, Tomoko Matsui, Chee Leong Soong, Eric Allain, Anders Vikso Nielsen, Hiroaki Udagawa, Ye Liu, Junxin Duan, Wenping Wu, Lene Nonboe Andersen
  • Publication number: 20110104779
    Abstract: The present invention relates to use of heat-stable carbonic anhydrase in CO2 extraction, e.g., from flue gas, natural gas or biogas. Furthermore, the invention relates to isolated polypeptides having carbonic anhydrase activity at elevated temperatures and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
    Type: Application
    Filed: January 11, 2011
    Publication date: May 5, 2011
    Applicant: Novozymes A/S
    Inventors: Martin Borchert, Paria Saunders
  • Publication number: 20110105384
    Abstract: The present invention relates to the use of polypeptides related to a Bacillus licheniformis polypeptide (amino acids 1-85 of SEQ ID NO: 2) as antimicrobial agents, for example in pharmaceutical applications, including veterinary applications, as well as for preservation, cleaning and disinfection of various surfaces, objects and substances. The polypeptides may in particular be used to treat textiles or laundry, e.g., in detergents, for reducing microbes on textile or laundry, and/or for odor reduction. The invention also relates to use of Bacillus strains producing these polypeptides as antimicrobial agents. Examples of microorganism inhibited by Lento are Gram positive bacterial strains, such as Bacillus cereus, and various species of Corynebacterium, Enterococcus, Micrococcus, Streptococcus, and Staphylococcus.
    Type: Application
    Filed: December 16, 2010
    Publication date: May 5, 2011
    Applicant: NOVOZYMES A/S
    Inventors: ERIK GORMSEN, DEBBIE YAVER
  • Publication number: 20110104141
    Abstract: The present invention relates to methods for preventing, removing, reducing, or disrupting biofilm present on a surface, comprising contacting the surface with an alpha-amylase derived from a bacterium.
    Type: Application
    Filed: November 29, 2010
    Publication date: May 5, 2011
    Applicants: Novozymes A/S, Novozymes North America, Inc.
    Inventors: Randy Deinhammer, Carsten Andersen
  • Patent number: 7935501
    Abstract: The invention relates to the use of co-expression of an antimicrobial agent and an enzyme, with a view to improving yield and/or overall production economy. Examples of antimicrobial agents are antimicrobial peptides such as lactoferricins and antimicrobial enzymes such as lysozyme and glucose oxidase, and examples of enzymes are endoglucanase, xylanase, phytase, protease, galactanase, mannanase, dextranase, alpha-galactosidase, pectate lyase, alpha-amylase and glucoamylase. A fusion product comprising the antimicrobial agent and the enzyme and a cleavable linker is novel, and can be used in animal feed and animal feed additives. The invention also describes the use of a protection domain wherein at least 50% of the amino acid residues comprised in the peptide protection domain are D (Asp) and/or E (Glu). The protection or quenching domain serves to temporarily and reversibly inactivate the antimicrobial peptide during the expression.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: May 3, 2011
    Assignee: Novozymes Pharma Biotec A/S
    Inventors: Ejner Bech Jensen, Hans-Henrik Kristensen Høgenhaug, Peter Kamp Hansen, Poul Erik Pedersen, Per Holse Mygind
  • Publication number: 20110099671
    Abstract: The present invention relates to variants of a parent cellobiohydrolase II. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: October 20, 2010
    Publication date: April 28, 2011
    Applicant: NOVOZYMES, INC.
    Inventor: MARK WOGULIS
  • Publication number: 20110097445
    Abstract: The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.
    Type: Application
    Filed: January 5, 2011
    Publication date: April 28, 2011
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Carsten Andersen, Lars Lehmann Hylling Christensen, Søren Flensted Lassen, Peter Rahbek Østergaard
  • Publication number: 20110097760
    Abstract: The present invention relates to a method for producing a casein hydrolysate using a microbial endopeptidase.
    Type: Application
    Filed: May 29, 2009
    Publication date: April 28, 2011
    Applicant: NOVOZYMES A/S
    Inventors: Gitte Budolfsen Lynglev, Per Munk Nielsen
  • Patent number: 7931925
    Abstract: The present invention relates to a process for producing cheese from enzyme-treated cheese milk, and the use of the resulting produced cheese as ingredient in food products. More particularly, the present invention relates to a process for producing cheese from cheese milk treated with a enzyme selected from the group of phospholipases, in particular phospholipase A1, A2 and B. Also, the present invention relates to a process for stabilizing the fat emulsion of a milk composition, e.g. cream, and the use of such stabilized milk composition, e.g. for the manufacturing of UHT-cream or cream liquor.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: April 26, 2011
    Assignee: Novozymes A/S
    Inventor: Per Munk Nielsen
  • Patent number: 7932073
    Abstract: The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: April 26, 2011
    Assignee: Novozymes, Inc.
    Inventors: Sarah Teter, Connie Ward, Joel Cherry, Aubrey Jones, Paul Harris, Jung Yi
  • Publication number: 20110091941
    Abstract: The invention relates to processes for hydrolyzing lignocellulose-containing material. The invention also relates to processes of producing fermentation products including a hydrolysis process of the invention.
    Type: Application
    Filed: July 3, 2009
    Publication date: April 21, 2011
    Applicant: Novozymes A/S
    Inventor: Hans Sejr Olsen
  • Publication number: 20110091950
    Abstract: The present invention relates to isolated polypeptides having alpha-glucuronidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: December 3, 2010
    Publication date: April 21, 2011
    Applicant: Novozymes A/S
    Inventors: Eva H. Hansen, Dominique A. Skovland, Hanne R. Soerensen
  • Publication number: 20110092409
    Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.
    Type: Application
    Filed: June 4, 2009
    Publication date: April 21, 2011
    Applicant: Novozymes A/S
    Inventors: Werner Besenmatter, Esben Peter Friis, Keith Gibson, Frank Winther Rasmussen, Michael Skjoet
  • Publication number: 20110092413
    Abstract: The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin.
    Type: Application
    Filed: November 2, 2010
    Publication date: April 21, 2011
    Applicant: Novozymes Biopharma DK A/S
    Inventors: Hans-Peter Hauser, Thomas Weimer, Val Romberg, Scott M. Kee, Darrell Sleep, Robert Charles Ladner, Arthur C. Ley
  • Publication number: 20110092408
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Application
    Filed: December 21, 2010
    Publication date: April 21, 2011
    Applicant: Novozymes A/S
    Inventors: Henriette Draborg, Peter Kamp Hansen, Mads Eskelund Bjornvad, Mads Nonegaard-Madsen, Mikael Mikkelsen
  • Publication number: 20110091601
    Abstract: The addition of a lipoxygenase and a lipolytic enzyme active on polar lipids to a dough has a synergistic effect on the volume and/or crumb color of an edible product made by leavening and heating the dough, e.g. by baking or steaming.
    Type: Application
    Filed: December 21, 2010
    Publication date: April 21, 2011
    Applicant: Novozymes A/S
    Inventors: Kim Borch, Luise Erlandsen, Morten Tovborg Jensen
  • Patent number: 7927857
    Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits altered properties, in particular improved thermal stability and/or increased specific activity.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: April 19, 2011
    Assignee: Novozymes A/S
    Inventors: Bjarne Ronfeldt Nielsen, Allan Svendsen, Henrik Pedersen, Jesper Vind, Hanne Vang Hendriksen, Torben Peter Frandsen
  • Publication number: 20110086132
    Abstract: A transgenic plant cell expressing a maltogenic amylase (such as Novamyl®) or a beta-amylase; a transgenic plant regenerated from said cell; seeds generated from such plant where said seeds comprise a maltogenic amylase or a beta-amylase and the use of said seeds, optionally in ground form, for catalyzing an industrial process, such as e.g. in baking. The maltogenic amylase providing an anti staling effect in bread produced from the seeds in question.
    Type: Application
    Filed: December 15, 2010
    Publication date: April 14, 2011
    Applicant: Novozymes A/S
    Inventors: Jack Bech Nielsen, Søren Kjaerulff
  • Publication number: 20110086407
    Abstract: The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substances and to nucleic acid constructs, vectors, and host cells comprising the genes as well as methods for producing biologically active substances encoded by the genes and to methods of using the isolated genes of the complete chromosome of Bacillus licheniformis.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 14, 2011
    Applicants: Novozymes A/S, Novozymes, Inc.
    Inventors: Randy Berka, Michael Rey, Preethi Ramaiya, Jens Tønne Andersen, Michael Dolberg Rasmussen, Peter Bjarke Olsen
  • Patent number: 7923232
    Abstract: The present invention relates to isolated polypeptides having phytase activity and isolated polynucleotides encoding the polypeptides. The polypeptides are related to a phytase derived from Hafnia alvei, the amino acid sequence of which is shown in the appended sequence listing as SEQ ID NO: 10. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides, in particular within animal feed.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: April 12, 2011
    Assignee: Novozymes A/S
    Inventors: Soeren Flensted Lassen, Carsten Sjoeholm, Lars Kobberoee Skov