Patents Assigned to NSC Technologies LLC
  • Regioselective .alpha.-hydrolysis of amino acid diesters using pig liver esterase
    Patent number: 5928909
    Abstract: The regioselective and chemoselective hydrolysis of an .alpha.-ester group of an amino acid diester using pig liver esterase enzyme (PLE) is disclosed. The amino acid diesters may be either N-protected or unprotected and the diester groups may be the same or different. In particular, the preparation of a number of .gamma.-ester glutamates and .beta.-ester aspartates are provided.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: July 27, 1999
    Assignee: NSC Technologies LLC
    Inventors: Indra Prakash, David J. Ager, David P. Pantaleone