Abstract: Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-?) in a subject in need thereof.
Type:
Application
Filed:
November 10, 2008
Publication date:
October 22, 2009
Applicant:
Nuada, Inc.
Inventors:
John R. Didsbury, Tatyana Dyakonov, Simon N. Haydar, Michael L. Jones, Francine F. Li, Christopher J. Markworth, Jessy Matthew, Frank J. Schoenen, Jan J. Scicinski, David Middlemiss, James F. Burns, Leonard A. Cabana, Glenn C. Collupy, David N. Vanvliet