Patents Assigned to Nuclea Biotechnologies LLC
  • ANTI-PHOSPHO-AKT ANTIBODIES
    Publication number: 20100092473
    Abstract: The present invention relates to antibodies that immunospecifically bind to phospho-Akt and certain p-Akt substrates. The invention encompasses human and humanized forms of the antibodies and their use in treating cancers and other proliferative disorders. The invention also relates to p-Akt-derived peptides useful for preparing the antibodies. Methods and compositions for detecting, diagnosing, treating or ameliorating a disease or disorder, especially cancer and other proliferative disorders using the present antibodies also are disclosed.
    Type: Application
    Filed: November 13, 2009
    Publication date: April 15, 2010
    Applicant: Nuclea Biotechnologies LLC
    Inventor: Patrick J. Muraca