Patents Assigned to Nucletron Operation B.V.
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Patent number: 8995616Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.Type: GrantFiled: December 22, 2011Date of Patent: March 31, 2015Assignee: Nucletron Operations B.V.Inventors: Johannes Simon van der Veen, Bas Woudstra, Johan Henning
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Publication number: 20140350325Abstract: An afterloading device for effectuating a brachytherapy treatment, comprising a first elongated flexible transport element, arranged to maneuver a radiation source between a storage position inside the afterloading device and a treatment position outside the afterloading device, the afterloading device further comprising a second elongated flexible transport element, having at least one transducer, the second transport element being arranged to move the at least one transducer between a first transducer position and a second transducer position.Type: ApplicationFiled: May 21, 2014Publication date: November 27, 2014Applicant: Nucletron Operations B.V.Inventors: Adriaan VAN APPELDOORN, Jeroen SCHUURMAN, Martin VAN BEEK, Finn SOLLEN, Johan HENNING, Arie Luite VISSCHER
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Patent number: 8834339Abstract: This invention relates to an assembly for performing brachytherapy treatment of tumour tissue in an animal body comprising at least a longitudinally extending intracavitary component and at least a guiding unit which extends at least partly parallel to said intracavitary component. Said guiding unit comprises at least one interstitial needle for guiding a radiation source into the tumour tissue. Said guiding unit is tubular over at least a longitudinal distance sufficient that in use a proximal end of said guiding unit is situated outside said body to be treated, while a distal end of said guiding unit is situated in situ close to or adjacent the tumour tissue.Type: GrantFiled: September 23, 2009Date of Patent: September 16, 2014Assignee: Nucletron Operations B.V.Inventors: Jean-Michel Hannoun-Levi, Cor Van De Wardt, Arie Luite Visscher, Dirk Binnekamp
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Publication number: 20140187849Abstract: An embodiment of the present disclosure is directed to a brachytherapy source assembly including a guiding wire and a brachytherapy capsule located at a distal end of the guiding wire. The capsule includes a chamber defined by a wall for holding a radioactive source. At least a portion of an exterior surface of the wall of the capsule includes at least one of a friction-reducing coating, a wear-resistant coating, and a wear-indication coating a coating.Type: ApplicationFiled: June 1, 2012Publication date: July 3, 2014Applicant: Nucletron Operations B.V.Inventors: Pier Bakker, Wim de Jager, Arie Luite Visscher, Henk Vreeken
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Patent number: 8744553Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.Type: GrantFiled: September 24, 2012Date of Patent: June 3, 2014Assignee: Nucletron Operations B.V.Inventors: Johann Kindlein, Dimos Baltas, Georgios Sakas, Frans Kulpers, Hans Martin Schot
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Publication number: 20140121443Abstract: Embodiments of the present disclosure relate to a modular applicator for enabling a brachytherapy treatment, comprising a central core and an outer sleeve, wherein the central core is adapted with a fixation mechanism for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.Type: ApplicationFiled: October 25, 2013Publication date: May 1, 2014Applicant: Nucletron Operations B.V.Inventors: Wilhelmus Petrus Martinus Maria van Erp, Tommy Robert Oscar Martens, Gaetan Stephan Marie van Wijck, Cor van de Wardt
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Publication number: 20140121444Abstract: A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core of the fixation element with respect to the central element.Type: ApplicationFiled: October 25, 2013Publication date: May 1, 2014Applicant: Nucletron Operations B.V.Inventors: Wilhelmus Petrus Martinus Maria van Erp, Tommy Robert Oscar Martens, Gaetan Stephan Marie van Wijck, Cor van de Wardt
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Publication number: 20140114115Abstract: Embodiments of the disclosure relate to a method for reconstructing a spatial position of a conduit arranged to accommodate a radiotherapeutic radioactive source. The method includes displacing an object emitting radiation inside the conduit prior to the administration of a treatment, detecting said radiation using detectors; generating data upon detecting the said radiation using a processor; and reconstructing the spatial position of the conduit by the processor based on the said data to identify a delivery path of the treatment.Type: ApplicationFiled: October 23, 2013Publication date: April 24, 2014Applicant: Nucletron Operations B.V.Inventor: Paulus Cornelis Hendrikus Maria Krechting
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Publication number: 20130102831Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.Type: ApplicationFiled: September 24, 2012Publication date: April 25, 2013Applicant: Nucletron Operations B.V.Inventor: Nucletron Operations B.V.
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Patent number: 8301228Abstract: The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm.Type: GrantFiled: January 25, 2011Date of Patent: October 30, 2012Assignee: Nucletron Operations B.V.Inventors: Johann Kindlein, Dimos Baltas, Georgios Sakas, Frans Kuipers, Hans Martin Schot
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Patent number: 8273007Abstract: An apparatus is described for transporting and positioning a capsule, in which a radioactive source is present, from a screened safe into an applicator to be temporarily placed in the body of the patient. The apparatus is provided with a safe for storing at least one capsule and with a larger number of applicators, which can be connected, via transport tubes, to passages in a switch-connecting plate, wherein the capsules, or a dummy instead of one of the capsules, can each, via their own tube and switch, independently of one another, be introduced into a transport tube selected by the respective switch and can be displaced therein independently of one another in a manner programmable with regard to location and residence time, by a transport wire slidable via a drive motor.Type: GrantFiled: December 2, 2009Date of Patent: September 25, 2012Assignee: Nucletron Operations B.V.Inventors: Eric van ′t Hooft, Libbe van Zwol, Joeri Tuijn