Patents Assigned to NUCORION PHARMACEUTICALS, INC.
  • 5-fluorouracil compounds
    Patent number: 11427550
    Abstract: The compounds are of the class of 5-fluorouracil derived acetal and hemiaminal ether compounds, useful in treating liver diseases and various types of cancer.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: August 30, 2022
    Assignee: NUCORION PHARMACEUTICALS, INC.
    Inventor: Lin Zhi
  • 5-fluorouridine monophosphate cyclic triester compounds
    Patent number: 10435429
    Abstract: Provided herein are 5-fluorouridine monophosphate cyclic triester compounds, their preparation and their uses, such as treating hepatocellular carcinoma and other types of cancer.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: October 8, 2019
    Assignee: Nucorion Pharmaceuticals, Inc.
    Inventor: Lin Zhi
  • Gemcitabine analogs
    Patent number: 10059733
    Abstract: Gemcitabine analogs, including monophosphorylated analogs, are described herein and are suitable for use in pharmaceutical compositions, kits and treatment methods. The treatment methods include treatment of viral infections, including, but not limited to, treatment of Hepatitis C Virus, and uncontrolled cellular proliferation, including cancer, such as, but not limited to, non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer, liver cancer, esophageal cancer and lymphoma.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: August 28, 2018
    Assignee: NUCORION PHARMACEUTICALS, INC.
    Inventors: Zucai Suo, David J. Taggart, Sheng Cao
  • Substituted gemcitabine bicyclic amide analogs and treatment methods using same
    Patent number: 10000521
    Abstract: In one aspect, the invention relates to substituted gemcitabine aryl amide analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating viral disorders and disorders of uncontrolled cellular proliferation using the compounds and compositions.
    Type: Grant
    Filed: March 15, 2014
    Date of Patent: June 19, 2018
    Assignee: Nucorion Pharmaceuticals, Inc.
    Inventors: Zucai Suo, Vinod P. Vyavhare, David J. Taggart
  • Substituted gemcitabine aryl amide analogs
    Patent number: 9744186
    Abstract: In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to substituted gemcitabine aryl amide analogs, methods of making the same, pharmaceutical compositions comprising same, methods of treating viral disorders and disorders of uncontrolled cellular proliferation using same.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: August 29, 2017
    Assignee: NUCORION PHARMACEUTICALS, INC.
    Inventor: Zucai Suo
  • Substituted gemcitabine aryl amide analogs
    Patent number: 9447137
    Abstract: In one aspect, the invention relates to substituted gemcitabine aryl amide analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating viral disorders and disorders of uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: September 20, 2016
    Assignee: NUCORION PHARMACEUTICALS, INC.
    Inventor: Zucai Suo