Patents Assigned to Nutrition 21
  • Patent number: 11471435
    Abstract: The present disclosure relates to the use of inositol-stabilized arginine silicate complexes (“ASI”) with the addition of free inositol (“I”) to form a composition ASI+I for improving cognitive functioning in humans, particularly video game players.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: October 18, 2022
    Assignee: NUTRITION 21, LLC
    Inventor: James R. Komorowski
  • Patent number: 11246886
    Abstract: The present application relates to the treatment of autism and autism spectrum disorders using biotin compositions.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: February 15, 2022
    Assignee: NUTRITION 21, LLC
    Inventor: James R. Komorowski
  • Patent number: 11191735
    Abstract: Methods for treating and/or preventing periodontal disease with arginine silicate are disclosed. Methods may include the steps of identifying an individual in need of treatment for, or in need of prevention of, periodontal disease and administering an effective amount of an arginine-silicate complex to said individual. Arginine silicate may also be used to ameliorate one or more symptoms of periodontal disease. In some aspects, arginine silicate may be used to restore gum health and/or stop or reverse recession of the gums and/or the loss of gum tissue in the oral cavity.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: December 7, 2021
    Assignee: NUTRITION 21, LLC
    Inventors: James R Komorowski, Kazim Sahin
  • Patent number: 11103000
    Abstract: Methods of manufacturing inositol-stabilized arginine-silicate (“ASI”) complexes with reduced or eliminated clumping and with increased solubility.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: August 31, 2021
    Assignee: NUTRITION 21, LLC
    Inventor: James R. Komorowski
  • Patent number: 10959971
    Abstract: The present disclosure relates to the use of inositol-stabilized arginine silicate complexes (“ASI”) with the addition of free inositol (“I”) to form a composition ASI+I for improving cognitive functioning in humans, particularly video game players.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: March 30, 2021
    Assignee: NUTRITION 21, LLC
    Inventor: James R. Komorowski
  • Patent number: 10183049
    Abstract: The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: January 22, 2019
    Assignee: NUTRITION 21, LLC
    Inventors: James R. Komorowski, Sara Perez Ojalvo
  • Patent number: 8198231
    Abstract: Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include ?-lactams and glycopeptides.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: June 12, 2012
    Assignee: Nutrition 21, Inc.
    Inventors: Michael Climo, Ellen Murphy, Gordon Archer
  • Publication number: 20120128794
    Abstract: Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.
    Type: Application
    Filed: November 18, 2011
    Publication date: May 24, 2012
    Applicant: NUTRITION 21, INC.
    Inventor: James R. Komorowski
  • Patent number: 8062677
    Abstract: Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first “fast-acting” chromium complex and a second “slow-acting” chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: November 22, 2011
    Assignee: Nutrition 21, Inc.
    Inventor: James R. Komorowski
  • Publication number: 20100129413
    Abstract: A method for treatment of a viral infection in a mammal comprising a step of administering a composition containing an amount of selenium (Se) effective to raise the serum level of the mammal to at least 15 ?g/L above baseline.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 27, 2010
    Applicant: NUTRITION 21, INC.
    Inventors: James Komorowski, Barry Hurwitz
  • Patent number: 7576132
    Abstract: A method for preventing and treating a variety of disease states and disorders is provided, comprising the administration of an arginine silicate inositol complex to an individual in the presence of medical therapy or absence of medical therapy. Examples of said disease states and disorders include bone and cartilage disorders and cardiovascular disease and its associated micro and macro vascular complications including infections and inflammation of all these diseases in combination or without. Advantageously, the amount of arginine silicate inositol complex administered per day is between about 2 mg/Kg body weight to 2,500 mg/Kg body weight or from a low dose to a higher dose to observe normal metabolic functions and healthy and the delivery is parenteral, oral or intravenous or topical by solid or liquid or both.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: August 18, 2009
    Assignee: Nutrition 21, Inc.
    Inventors: Vijaya Juturu, James R. Komorowski
  • Publication number: 20060246055
    Abstract: Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include ?-lactams and glycopeptides.
    Type: Application
    Filed: June 2, 2006
    Publication date: November 2, 2006
    Applicant: Nutrition 21
    Inventors: Michael Climo, Ellen Murphy, Gordon Archer
  • Patent number: 7122514
    Abstract: Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include ?-lactams and glycopeptides.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: October 17, 2006
    Assignee: Nutrition 21, Inc.
    Inventors: Michael Climo, Ellen Murphy, Gordon Archer
  • Patent number: 7078377
    Abstract: Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include ?-lactams and glycopeptides.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: July 18, 2006
    Assignee: Nutrition 21, Inc.
    Inventors: Michael Climo, Ellen Murphy, Gordon Archer
  • Patent number: 6809115
    Abstract: A composition for treating insulin-dependent diabetes, reducing body fat, improving insulin sensitivity, reducing hyperglycemia, and reducing hypercholesterolemia with at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is disclosed. A method of treating a subject suffering from insulin-dependent diabetes by administering a composition that includes at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol is similarly provided. The administration of a composition containing an effective dose of at least one chromium complex and a conjugated fatty acid or conjugated fatty alcohol for the treatment of obesity is likewise provided.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: October 26, 2004
    Assignee: Nutrition 21, Inc.
    Inventors: David P. Katz, James R. Komorowski, Danielle Greenberg
  • Patent number: 6344444
    Abstract: The present invention is directed to an arginine-silicate complex and its use in the prevention and treatment of atherosclerosis, as a dietary supplement, and for promotion of structural integrity of bones and cartilage.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: February 5, 2002
    Assignee: Nutrition 21
    Inventors: Mark F. McCarty, Jan Zielinski
  • Patent number: 6329361
    Abstract: A method for stabilizing blood glucose levels and reducing the hyperglycemia associated with Type II diabetes. Synthetic chromic tripicolinate is administered either orally or parenterally to a human in need thereof at a dosage of between about 1,000 amd 10,000 micrograms per day.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: December 11, 2001
    Assignee: Nutrition 21
    Inventor: Mark F. McCarty
  • Patent number: 6203823
    Abstract: Use of calcium taurate as an antihypertensive agent and dietary supplement. The compound is prepared by reacting taurine and calcium in a 2:1 molar ratio. The resulting mixture is diluted with alcohol and the remaining clear filtrate is crystallized. Calcium taurate is taken orally as a nutritional supplement or antihypertensive agent, and can be used as an adjuvant to conventional antihypertensive drugs.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: March 20, 2001
    Assignee: Nutrition 21
    Inventor: Mark F. McCarty
  • Patent number: 6156735
    Abstract: The present invention is directed to an arginine-silicate complex and its use in the prevention and treatment of atherosclerosis, as a dietary supplement and for promotion of structural integrity of bones and cartilage.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: December 5, 2000
    Assignee: Nutrition 21
    Inventors: Mark F. McCarty, Jan Zielinski
  • Patent number: RE39480
    Abstract: A method for treating Type II diabetes by administering to an affected individual a combination of chromic tripicolinate and biotin. The two compounds are administered orally or parenterally at in daily dosages which provide between 50 and 1,000 ?g of chromium and between 25 ?g and 200 mg biotin, the amounts of chromium and biotin being selected together to provide a greater than additive effect.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: January 23, 2007
    Assignee: Nutrition 21, Inc.
    Inventor: Mark F. McCarty