Patents Assigned to NuvOx Pharma LLC
  • Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
    Patent number: 11857627
    Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms.
    Type: Grant
    Filed: November 25, 2022
    Date of Patent: January 2, 2024
    Assignee: NuvOx Pharma LLC
    Inventor: Evan C. Unger
  • Adjusting particle size in fluorocarbon nanoemulsions
    Patent number: 11826319
    Abstract: The invention provides devices and methods for adjusting particle size in nanoemulsions of fluorocarbons and perfluorocarbons (e.g., perfluoropentane and perfluorohexane) via sonication (e.g., ultrasonication).
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: November 28, 2023
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Edmund Marinelli
  • Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
    Patent number: 11534492
    Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms.
    Type: Grant
    Filed: February 7, 2021
    Date of Patent: December 27, 2022
    Assignee: NuvOx Pharma LLC
    Inventor: Evan C. Unger
  • Compositions of fluorocarbon nanoemulsion, and methods of preparation and use thereof
    Patent number: 11304899
    Abstract: The invention provides novel compositions of fluorocarbon nanoemulsions comprising one or more of fluorosurfactants and phospholipids, and methods of preparation and use thereof for enhanced oxygen delivery.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: April 19, 2022
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Edmund R. Marinelli
  • Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
    Patent number: 10946097
    Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms.
    Type: Grant
    Filed: August 24, 2019
    Date of Patent: March 16, 2021
    Assignee: NuvOx Pharma LLC
    Inventor: Evan C. Unger
  • Adjusting particle size in fluorocarbon nanoemulsions
    Patent number: 10780060
    Abstract: The invention provides devices and methods for adjusting particle size in nanoemulsions of fluorocarbons and perfluorocarbons (e.g., perfluoropentane and perfluorohexane) via sonication (e.g., ultrasonication).
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: September 22, 2020
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Edmund Marinelli
  • Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
    Patent number: 10456468
    Abstract: A fluorocarbon emulsion in water for use in fractionated radiotherapy and chemotherapy, wherein said fluorocarbon comprises between 4 and 8 carbon atoms.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: October 29, 2019
    Assignee: NuvOx Pharma LLC
    Inventor: Evan C. Unger
  • Microbubble compositions, method of making same, and method using same
    Patent number: 10279053
    Abstract: A method of forming a plurality of microbubbles, wherein the method disposes in a sealed container comprising a first volume at ambient pressure, a second volume of a mixture comprising one or more microbubble stabilizing materials. The first volume is greater than said second volume. The method further comprises sealing said container, introducing a gas into said sealed container, and shaking the container to form said plurality of microbubbles.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: May 7, 2019
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Patrick W. Hendon
  • Buffered oxygen therapeutics
    Patent number: 10166200
    Abstract: An oxygen therapeutic composition, which includes a perfluorocarbon material having a boiling point of about 4 degrees Celsius to about 60 degrees Celsius, a lipid; a viscosity modifier; a buffer.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: January 1, 2019
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Edmund R. Marinelli
  • Buffered oxygen therapeutic
    Patent number: 9700523
    Abstract: An oxygen therapeutic composition, which includes a perfluorocarbon material having a boiling point of about 4 degrees Celsius to about 60 degrees Celsius, a lipid; a viscosity modifier; a buffer.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: July 11, 2017
    Assignee: NuvOx Pharma LLC
    Inventors: Evan C. Unger, Ed Marinelli