Abstract: Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object.

Abstract: A system and method for reconstructing an image of a target object using an iterative reconstruction technique can include a machine learning model as a regularization filter (100). An image data set for a target object generated using an imaging modality can be received, and an image of the target object can be reconstructed using an iterative reconstruction technique that includes a machine learning model as a regularization filter (100) used in part to reconstruct the image of the target object. The machine learning model can be trained prior to receiving the image data using learning datasets that have image data associated with the target object, where the learning datasets providing objective data for training the machine learning model, and the machine learning model can be included in the iterative reconstruction technique to introduce the object features into the image of the target object being reconstructed.

Abstract: A technology for reconstructing an image of a three-dimensional object. In one example, a projection image dataset can be obtained from an imaging data detector and a reduced image dataset that has a lower quantity of data as compared to a quantity of data of the projection image dataset can be generated from the projection image dataset. An image remainder dataset can be generated to indicate an image difference between the projection image dataset and the reduced image dataset. A first scale image reconstruction of the three-dimensional object can be generated using the reconstruction technique and the reduced image dataset, and a second scale image reconstruction of the three-dimensional object can be generated using the iterative reconstruction technique and the image remainder dataset.

Abstract: Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object.

Abstract: Imaging systems and methods for rapidly generating reconstruction image data of an object while allowing access to the object during imaging. In some embodiments, the system may comprise at least one radiation source that moves along a path, which path may be defined by an enclosed gantry, and emits radiation toward at least one radiation detector. The radiation source(s) and the radiation detector may be positioned such that at least a portion of an object, such as a portion of a patient's anatomy, can be positioned in between the plurality of radiation sources and the radiation detector to facilitate generation of the reconstruction image data.

Abstract: Imaging systems and methods for rapidly generating reconstruction image data of an object while allowing access to the object during imaging. In some embodiments, the system may comprise at least one radiation source that moves along a path, which path may be defined by an enclosed gantry, and emits radiation toward at least one radiation detector. The radiation source(s) and the radiation detector may be positioned such that at least a portion of an object, such as a portion of a patient's anatomy, can be positioned in between the plurality of radiation sources and the radiation detector to facilitate generation of the reconstruction image data.