Patents Assigned to NVIP Pty Ltd
  • ANTI-NERVE GROWTH FACTOR ANTIBODIES AND METHODS OF PREPARING AND USING THE SAME
    Publication number: 20160272701
    Abstract: A method of preparing an antibody suitable for use in a feline is provided. Also provided are chimeric and felinised antibodies which specifically bind to feline neuronal growth factor (NGF) and neutralise the ability of feline NGF to bind to the p75 or TrkA feline NGF receptor. The invention extends to nucleic acids encoding same and to methods of treating pain and arthritis in a feline using said antibodies and/or nucleic acids.
    Type: Application
    Filed: March 28, 2016
    Publication date: September 22, 2016
    Applicant: NVIP Pty Ltd
    Inventor: David Gearing
  • Anti-nerve growth factor antibodies and methods of preparing and using the same
    Patent number: 9328164
    Abstract: A method of preparing an antibody suitable for use in a feline is provided. Also provided are chimeric and felinized antibodies which specifically bind to feline neuronal growth factor (NGF) and neutralize the ability of feline NGF to bind to the p75 or TrkA feline NGF receptor. The invention extends to nucleic acids encoding same and to methods of treating pain and arthritis in a feline using said antibodies and/or nucleic acids.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: May 3, 2016
    Assignee: NVIP PTY LTD
    Inventor: David Gearing
  • TUMOUR NECROSIS FACTOR RECEPTOR FUSION PROTEINS AND METHODS OF USING THE SAME
    Publication number: 20150037333
    Abstract: A chimeric fusion polypeptide is provided comprising an extracellular domain of a canine TNF receptor p60 or p80 polypeptide conjoined to an Fc region of a canine IgG immunoglobulin heavy chain. The chimeric fusion polypeptide may be used in the treatment or prevention of conditions in canines mediated by TNF expression.
    Type: Application
    Filed: February 22, 2013
    Publication date: February 5, 2015
    Applicant: NVIP Pty Ltd
    Inventors: Alexander Drew, David Gearing
  • CANINISED TUMOUR NECROSIS FACTOR ANTIBODIES AND METHODS OF USING THE SAME
    Publication number: 20140294815
    Abstract: Caninised and chimeric antibodies and antigen binding fragments thereof which bind specifically to canine tumour necrosis factor and inhibit the ability of canine TNF to bind to the TNFR1 receptor are provided. The invention further extends to nucleic acids encoding same and to methods of treating chronic inflammatory disease such as arthritis in a canine using said antibodies and/or nucleic acids.
    Type: Application
    Filed: August 29, 2012
    Publication date: October 2, 2014
    Applicant: NVIP Pty Ltd
    Inventor: David Gearing