Abstract: The present invention concerns a prosthetic heart valve for supporting or replacing a non- or malfunctioning native heart valve, the prosthetic heart valve comprising an expandable generally tubular stent support, having an inner surface and an outer surface, and comprising a valve element, having an outer surface, an inner surface, and comprising a plurality of sealing elements, wherein the sealing elements are—spaced apart from one another—circumferentially attached to the outer surface of the valve element and form a lip-shaped element radially protruding from the outer surface of the valve element, wherein the valve element is mounted on the inner surface of the stent support.

Abstract: The present invention concerns an intraluminal vascular prosthesis for implantation into the heart and/or cardiac vessels of a patient, in particular for anchoring in the region of the cardiac valve leaflets. The vascular prosthesis comprises a stent support and a prosthesis material at least partially covering the stent support, such, that a covered proximal portion and a non-covered distal portion are formed. Furthermore, the vascular prosthesis has at least one elongate wire-shaped anchoring structure at the proximal end, which is substantially loop-shaped and which is fixed at two ends to the stent support and which is positioned with its proximal end in the form of a loop pointing in the proximal direction and projecting beyond the proximal end of the stent support.

Abstract: The invention relates to a heart valve prosthesis for percutaneous replacement of a tricuspid valve including a stent-type support structure and a biological heart valve; the stent-type support structure can autonomously expand from a radially compressed state into a radially expanded state and includes a fluid-tight cover which extends like a tube over at least some portions of the support structure; the heart valve is arranged in a lateral opening in the support structure. Embodiments further relate to a system including a heart valve prosthesis of said type.

Abstract: A prosthetic heart valve system and a delivery system therefor, the prosthetic heart valve system comprising a heart valve element with expandable generally tubular stent support forming a wire frame, wherein the tubular stent support comprises a plurality of adjacent rows of interconnected, substantially diamond-shaped cell structures extending, along and in parallel to the longitudinal direction, between the proximal end and distal end, and wherein the stent support, in a medial portion, comprises a circumferential row of a plurality of wire anchor structures which wire anchor structures are spaced from one another and attached to the wire frame and which, in respect to the longitudinal axis of the stent support, at least partially protrude outward at an angle ?. The prosthetic heart valve system may also comprise a stent(graft)-element.

Abstract: The present invention relates to a deployment system (10) for deploying an expandable cardiac valve prosthesis. The deployment system comprises a first tube (11) being designed to carry an expandable cardiac valve prosthesis; further, a tip (13), being firmly connected to the first tube at a distal end of the first tube, wherein the tip is designed such, that it detachably accommodates and holds a proximal end (21) of a cardiac valve prosthesis (20); a sheath (15) designed to be disposed over and holding the prosthesis (20) in a compressed state, and a first actuating mechanism (16) being linked to the sheath (15) and being slidable in a proximal direction for stepwise retracting the sheath (15).

Abstract: A device for implantation into the heart of a mammal and a method for treating tricuspid regurgitation using the device. The device includes two tubular stent members separated by a stent graft member which has a functional stented valve member attached thereto allowing unidirectional blood flow from the vena cava into the right atrium.

Abstract: An implantable device for treating mitral valve regurgitation, the device being configured to expand from a compressed state into an expanded state. The device comprises a stent element consisting of (i) an atrial anchoring stent-portion, and (ii) a valve-carrying stent-portion being fixedly connected with one another, and a valve-element. The atrial anchoring stent-portion has a balloon-like shape and the valve-carrying stent-portion has a cylindrical shape, such, that the valve-carrying stent-portion is positioned intra-annular without contacting the annulus of a native mitral valve.

Abstract: The present invention relates to a prosthetic mitral valve device for implanting at the native mitral valve region of a heart. The prosthetic mitral valve coaptation enhancement device comprises a main body consisting of a stentframe and a valve element attached thereto, wherein the main body has a sealing section and a valve-bearing section, the valve-bearing section; the shape of the sealing section of the main body, in the compressed state, has a form that is adapted to the coaptation zone of the native mitral valve during systole, and the sealing section of the main body, the radial rigidity of the stentframe is lower than the radial rigidity of the valve-bearing section; the prosthetic mitral valve coaptation enhancement device further comprises at least one anchoring element, which anchoring element is coupled to the main body and is capable to anchor the main body within the native mitral valve region of a heart.

Abstract: The present invention relates to a prosthetic heart valve, the prosthetic heart valve comprising a generally tubular stent support and a valve structure. The stent support comprises multiple rows of diamond-shaped cell structures and crowns at its distal and proximal end, as well as three V-shaped openings which open towards the distal end of stent support.

Abstract: An implantable device for treating mitral valve regurgitation, the device being configured to expand from a compressed state into an expanded state. The device comprises a stent element consisting of (i) an atrial anchoring stent-portion, and (ii) a valve-carrying stent-portion being fixedly connected with one another, and a valve-element. The atrial anchoring stent-portion has a balloon-like shape and the valve-carrying stent-portion has a cylindrical shape, such, that the valve-carrying stent-portion is positioned intra-annular without contacting the annulus of a native mitral valve.

Abstract: The present invention concerns a cardiac valve prosthesis system (10; 40) for implantation into the body of a mammal. The prosthesis system (19; 40) comprises a valve (16) mounted on an stent element (18) to form a stented valve element (12), and an anchoring element (14) to be arranged within the aorta of the mammal to be treated with the prosthesis and spaced-apart form the stented valve element (12). Further, the anchoring element (14) comprises a cylindrical tube element composed of fabric (22) supported by a metal mesh, and the stented valve element (12) and the anchoring element (14) represent two constructional distinctive elements being associated by ligament-like connecting means (30; 50), such, that the connecting region (28) between the stented valve element (12) and the anchoring element (14) is generally free from foreign material.

Abstract: The present invention relates to a deployment system (10) for deploying an expandable cardiac valve prosthesis. The deployment system comprises a first tube (11) being designed to carry an expandable cardiac valve prosthesis; further, a tip (13), being firmly connected to the first tube at a distal end of the first tube, wherein the tip is designed such, that it detachably accommodates and holds a proximal end (21) of a cardiac valve prosthesis (20); a sheath (15) designed to be disposed over and holding the prosthesis (20) in a compressed state, and a first actuating mechanism (16) being linked to the sheath (15) and being slidable in a proximal direction for stepwise retracting the sheath (15).

Abstract: The present invention concerns a cardiac valve prosthesis system (10; 40) for implantation into the body of a mammal. The prosthesis system (19; 40) comprises a valve (16) mounted on an stent element (18) to form a stented valve element (12), and an anchoring element (14) to be arranged within the aorta of the mammal to be treated with the prosthesis and spaced-apart form the stented valve element (12). Further, the anchoring element (14) comprises a cylindrical tube element composed of fabric (22) supported by a metal mesh, and the stented valve element (12) and the anchoring element (14) represent two constructional distinctive elements being associated by ligament-like connecting means (30; 50), such, that the connecting region (28) between the stented valve element (12) and the anchoring element (14) is generally free from foreign material.