Patents Assigned to NY State Psychiatric Institute
  • Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 11261199
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: March 1, 2022
    Assignees: The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
  • Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 11230558
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: January 25, 2022
    Assignees: The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
  • Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 11008341
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: May 18, 2021
    Assignees: The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
  • Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 10865214
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: December 15, 2020
    Assignees: The Trustees of Columbia University in they City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
  • Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 10626124
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: April 21, 2020
    Assignees: The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng
  • Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
    Patent number: 10487091
    Abstract: The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: November 26, 2019
    Assignees: The Trustees of Columbia University in the City of New York, NY State Psychiatric Institute
    Inventors: Kirsten Alison Rinderspacher, Wai Yu, Karen Duff, Donald Landry, Shi-Xian Deng