Patents Assigned to Nymox Pharmaceutical Corporation
  • Publication number: 20120114679
    Abstract: The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 10, 2012
    Applicant: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Patent number: 8067378
    Abstract: The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: November 29, 2011
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Publication number: 20090286742
    Abstract: The invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on peptides comprising a part of the amino acid sequence of a neural thread protein.
    Type: Application
    Filed: June 15, 2009
    Publication date: November 19, 2009
    Applicant: NYMOX PHARMACEUTICAL CORPORATION
    Inventors: PAUL AVERBACK, JACK GEMMELL
  • Publication number: 20090022743
    Abstract: The invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on peptides comprising a part of the amino acid sequence of a neural thread protein.
    Type: Application
    Filed: July 11, 2008
    Publication date: January 22, 2009
    Applicant: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Patent number: 7408021
    Abstract: The invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on peptides comprising a part of the amino acid sequence of a neural thread protein.
    Type: Grant
    Filed: October 12, 2004
    Date of Patent: August 5, 2008
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Patent number: 7317077
    Abstract: The invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on peptides comprising a part of the amino acid sequence of a neural thread protein.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: January 8, 2008
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Patent number: 7259232
    Abstract: The invention is directed to preferred repeat sequences of Neural Thread Protein (NTP), peptides, mimetics, antibodies, and nucleic acids of the preferred sequences, and diagnostic and therapeutic methods of using such preferred NTP sequences.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: August 21, 2007
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Judith Fitzpatrick, Paul Averback, Maggie Focht, Riza Bibiano
  • Patent number: 7241738
    Abstract: The present invention relates to peptides, compositions, and methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using proteins (and peptides derived from the amino acid sequences of such proteins), the amino acid sequence of which includes at least one amino acid sequence derived from neural thread proteins and other related molecules.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: July 10, 2007
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Publication number: 20050032704
    Abstract: The invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on peptides comprising a part of the amino acid sequence of a neural thread protein.
    Type: Application
    Filed: October 12, 2004
    Publication date: February 10, 2005
    Applicant: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Publication number: 20030054990
    Abstract: The present invention is directed to methods of treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using neural thread proteins and related molecules.
    Type: Application
    Filed: March 8, 2002
    Publication date: March 20, 2003
    Applicant: Nymox Pharmaceutical Corporation
    Inventor: Paul Averback
  • Patent number: 6461608
    Abstract: The present invention is directed to novel bacteriophage compositions useful in treating food products to prevent bacterial contamination.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: October 8, 2002
    Assignee: Nymox Pharmaceutical Corporation
    Inventors: Paul Averback, Jack Gemmell
  • Patent number: 6309892
    Abstract: DMS present in the brain of individuals susceptible to cerebral amyloidosis disintegrate into DMS components to form cerebral amyloid plaques and other DMS components that are removed from the brain via circulating bodily fluids. Detecting the presence of these removed DMS components and/or antibodies thereto in circulating bodily fluids provides a diagnostic mechanism to determine the onset of cerebral amyloid plaque formation. Detecting the presence of these removed DMS components and/or antibodies thereto in circulating bodily fluids also provides a diagnostic mechanism to determine the efficacy of treatment regimes for preventing cerebral amyloid plaque formation. Antibodies also can be raised against isolated DMS components and subsequently utilized in a diagnostic method capable of detecting the onset of cerebral amyloid plaque formation.
    Type: Grant
    Filed: June 10, 1996
    Date of Patent: October 30, 2001
    Assignee: Nymox Pharmaceutical Corporation
    Inventor: Paul Averback
  • Patent number: 5955285
    Abstract: Dense microspheres can be extracted and purified to substantial homogeneity from mammalian brain tissue, and used in the screening of therapies for potential effectiveness in impeding the formation of amyloid fibrils associated with Alzheimer's disease and other forms of cerebral amyloidosis. Compounds that, at in-tissue concentrations of 10.sup.-5 M or less, inhibit amyloid formation in a test animal injected intracerebrally with dense microspheres are particularly useful in inhibiting treating cerebral amyloidosis.
    Type: Grant
    Filed: October 4, 1996
    Date of Patent: September 21, 1999
    Assignee: Nymox Pharmaceutical Corporation
    Inventor: Paul Averback