Patents Assigned to NYU
  • Imaging agents for protein misfolding
    Publication number: 20100279340
    Abstract: Charged and neutral small fluorescent molecules based upon the styryl scaffold are useful as imaging agents for misfolded proteins such as amyloid plaque. Charged molecules are prepared using pyrrolidine catalyzed reactions by solution-phase synthesis. Neutral styryl molecules are prepared using acetic anhydride catalyzed reactions, Horner-Emmons reactions or Wittig reactions.
    Type: Application
    Filed: February 11, 2008
    Publication date: November 4, 2010
    Applicant: NYU
    Inventors: Thomas Wisniewski, Jaeki Min, Qian Li, Young-Tae CHANG