Abstract: The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various embodiments, the preparations, devices, systems and methods enable sustained drug release for the treatment or prevention of hearing loss, infections, and other pathological conditions of cochlea and inner ear.
Type:
Grant
Filed:
May 13, 2016
Date of Patent:
April 5, 2022
Assignee:
O-Ray Pharma, Inc.
Inventors:
William H. Slattery, Thomas Smith, Erik Pierstorff, Marc M. Baum
Abstract: The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various embodiments, the preparations, devices, systems and methods enable sustained drug release for the treatment or prevention of hearing loss, infections, and other pathological conditions of cochlea and inner ear.
Type:
Application
Filed:
May 13, 2016
Publication date:
September 1, 2016
Applicant:
O-Ray Pharma, Inc.
Inventors:
William H. Slattery, Thomas Smith, Erik Pierstorff, Marc M. Baum
Abstract: The present invention provides for methods of producing a drug product that is capable of providing controlled and sustained release of a drug. Particularly, the release of the drug will be to a specific tissue area in the body. The methods include, but are not limited to, providing an impermeable casing with an open end, placing a compressed drug pellet into the impermeable casing, coating the open end of the impermeable casing with a permeable layer to create a release window for the drug product to provide controlled and/or sustained release of the drug.
Abstract: The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various embodiments, the preparations, devices, systems and methods enable sustained drug release for the treatment or prevention of hearing loss, infections, and other pathological conditions of cochlea and inner ear.
Type:
Application
Filed:
February 27, 2013
Publication date:
February 12, 2015
Applicant:
O-RAY PHARMA, INC.
Inventors:
William H. Slattery, Thomas Smith, Erik Pierstorff, Marc M. Baum