Patents Assigned to Obschestvo s ogranichennoy otvetstvennostyu "SEMIOTIK"
  • Publication number: 20130288928
    Abstract: The invention relates to glycan arrays with quantified levels of glycan expression and a method for fabricating thereof. The method comprises quantitatively reacting an ?-aminoalkylglycan with an activated polymer of an acrylic acid derivative to obtain glycoconjugated polymer or copolymer and covalently attaching the (co)polymer to a functionalized substrate. The glycan arrays according to the invention comprise an co-aminoalkylglycan covalently attached to a functionalized substrate via a fluorescently labeled (co)polymer of an acrylic acid derivative. The copolymer of an acrylic acid derivative may comprise fluorescein cadaverine as a fluorescent label or lysine or aminated PEG. The functionalized substrate is selected from an epoxylated and aminated glass or plastic. The invention also provides a fluorescently labeled co-aminoalkylglycan conjugated polymer of an acrylic acid derivative for use in the fabrication of glycan arrays.
    Type: Application
    Filed: December 30, 2010
    Publication date: October 31, 2013
    Applicant: Obschestvo s ogranichennoy otvetstvennostyu "SEMIOTIK"
    Inventors: Nikolay Vladimirovich Bovin, Nadezhda Vladimirovna Shilova