Patents Assigned to Ochanomizu University
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Publication number: 20240132669Abstract: The present invention provides a polyimide compound represented by formula (I): wherein Ar1 is a phenylene group substituted with one or more substituents, or an indolylene group optionally substituted with one or more substituents, Ar2 is a phenylene group substituted with one or more substituents, or an indolylene group optionally substituted with one or more substituents, the substituent is a group selected from a C1-6 alkyl group, a C1-6 alkoxy group, and a halogen atom, A1 is a linear or branched C4-16 perfluoroalkylene group, A2 is an aliphatic or aromatic bisimide-N?,N-diyl, and n1 is any integer.Type: ApplicationFiled: February 7, 2022Publication date: April 25, 2024Applicant: OCHANOMIZU UNIVERSITYInventors: Tomoko Yajima, Tadashi Kanbara
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Publication number: 20240124619Abstract: A method for producing a fluorine-containing polymer of the present disclosure includes reacting a polymer comprising a unit represented by the following Formula (I) with a fluorine-containing compound represented by the following Formula (II), to obtain a fluorine-containing polymer comprising a unit represented by the following Formula (III).Type: ApplicationFiled: August 14, 2023Publication date: April 18, 2024Applicant: OCHANOMIZU UNIVERSITYInventors: Tadashi Kanbara, Tomoko Yajima
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Publication number: 20230108750Abstract: It is an object of the present invention to identify a novel analog of carbacyclic phosphatidic acid that is a cyclic phosphatidic acid derivative, and to clarify the physiological activity thereof. According to the present invention, a compound represented by the following formula (1) is provided: wherein R represents a linear or branched alkyl group containing 1 to 30 carbon atoms, a linear or branched alkenyl group containing 2 to 30 carbon atoms, or a linear or branched alkynyl group containing 2 to 30 carbon atoms, and these groups may optionally comprise a cycloalkane ring or an aromatic ring; and M represents a hydrogen atom or a counter cation.Type: ApplicationFiled: November 20, 2020Publication date: April 6, 2023Applicant: OCHANOMIZU UNIVERSITYInventors: Kimiko MUROFUSHI, Mari GOTOH, Keiko FUKASAWA, Junken AOKI
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Publication number: 20210054174Abstract: A silsesquioxane compound represented by the following formula (I): (RaSiO1.5)n, wherein Ra is, each independently at each occurrence, Rb or Rc; provided that at least one Ra is Rb; Rb is —R1—CF2—R2—R3; R1 is a divalent group; R2 is a divalent polymer chain; R3 is a halogen atom or a hydrogen atom; Rc is a hydrogen atom, an alkyl group, a phenyl group, or —(OSiR152)j—R15; R15 is, each independently at each occurrence, a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; j is, each independently at each occurrence, an integer of 1 to 3; and n is an arbitrary integer.Type: ApplicationFiled: November 5, 2020Publication date: February 25, 2021Applicants: OCHANOMIZU UNIVERSITY, DAIKIN INDUSTRIES, LTD.Inventors: Tomoko Yajima, Moeka Sano, Tadashi Kanbara, Tsuyoshi Noguchi
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Publication number: 20210054004Abstract: An iodine compound represented by formula (3) and a polymerization inhibitor including the iodine compound, wherein R21 to R25 are as defined herein, X1 is an n1-valent group, and n1 is an integer of 1 to 10:Type: ApplicationFiled: November 5, 2020Publication date: February 25, 2021Applicants: OCHANOMIZU UNIVERSITY, DAIKIN INDUSTRIES, LTD.Inventors: Tomoko YAJIMA, Tadashi KANBARA, Tsuyoshi NOGUCHI
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Patent number: 10745524Abstract: The present invention provides a fluorine-containing, silicon-containing compound of formula (I): T1-(A-B)n-T2 which is useful as an additive.Type: GrantFiled: January 20, 2017Date of Patent: August 18, 2020Assignees: OCHANOMIZU UNIVERSITY, DAIKIN INDUSTRIES, LTD.Inventors: Tomoko Yajima, Kana Sasahara, Tadashi Kanbara, Tsuyoshi Noguchi
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Patent number: 10413559Abstract: It is an object of the present invention to provide a novel therapeutic agent for demyelinating disease which has an action to suppress demyelination of nerve axons. According to the present invention, a therapeutic agent for demyelinating disease which comprises cyclic phosphatidic acids, carba-cyclic phosphatidic acids, thia-cyclic phosphatidic acids, or a salt thereof is provided.Type: GrantFiled: January 28, 2014Date of Patent: September 17, 2019Assignees: OCHANOMIZU UNIVERSITY, SAITAMA MEDICAL UNIVERSITYInventors: Kimiko Murofushi, Mari Gotoh, Kei Maruyama, Keisuke Yoshikawa, Shinji Yamamoto
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Publication number: 20190023851Abstract: The present invention provides a fluorine-containing, silicon-containing compound of formula (I): T1-(A-B)n-T2 which is useful as an additive.Type: ApplicationFiled: January 20, 2017Publication date: January 24, 2019Applicants: OCHANOMIZU UNIVERSITY, DAIKIN INDUSTRIES, LTD.Inventors: Tomoko YAJIMA, Kana SASAHARA, Tadashi KANBARA, Tsuyoshi NOGUCHI
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Publication number: 20170160409Abstract: A solid scintillator member is provided in the internal space of a container. The scintillator member is an aggregate of a plurality of pellets. The internal space also confines a gas produced through the vaporization of a liquid sample containing a radioactive substance. When radiation emitted from a plurality of particles within the gas reaches the scintillator member, light is generated. That light is detected by a pair of photomultipliers. A plurality of particles may be produced outside of the container and introduced into the container.Type: ApplicationFiled: July 17, 2015Publication date: June 8, 2017Applicants: OCHANOMIZU UNIVERSITY, HITACHI, LTD.Inventors: Etsuko FURUTA, Yuka KATO, Kiyoshi OGIWARA
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Publication number: 20150352132Abstract: It is an object of the present invention to provide a novel therapeutic agent for demyelinating disease which has an action to suppress demyelination of nerve axons. According to the present invention, a therapeutic agent for demyelinating disease which comprises cyclic phosphatidic acids, carba-cyclic phosphatidic acids, thia-cyclic phosphatidic acids, or a salt thereof is provided.Type: ApplicationFiled: January 28, 2014Publication date: December 10, 2015Applicants: OCHANOMIZU UNIVERSITY, SAITAMA MEDICAL UNIVERSITYInventors: Kimiko MUROFUSHI, Mari GOTOH, Kei MARUYAMA, Keisuke YOSHIKAWA, Shinji YAMAMOTO
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Patent number: 8831271Abstract: To provide a detection device capable of, e.g., obtaining a list of genes whose expressions are commonly changed in response to administration of a specific drug or drugs, based on consideration of relationship (e.g., interacting relationship among genes) among genes, a list of proteins whose expressions are commonly changed in response to administration of a specific drug or drugs, based on consideration of relationship (e.g., interacting relationship among proteins) among proteins, and a list of users who purchased an identical product or products, based on consideration of relationship (e.g., friendship) among users, and so forth. A graph data obtaining unit (20) obtains graph data indicating a graph including a plurality of vertexes. A vertex data obtaining unit (22) obtains vertex data that correlates an information item to a vertex.Type: GrantFiled: October 7, 2009Date of Patent: September 9, 2014Assignee: Ochanomizu UniversityInventors: Jun Sese, Mio Seki
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Patent number: 8553880Abstract: The pseudorandom number generating system repeatedly performs simple transformation of a non-secure pseudorandom number sequence that may be generated quickly, and thus may quickly generate a highly secure pseudorandom number sequence having a long period. Furthermore, the encryption system and the decryption system do not generate a large encryption function difficult to be deciphered based on a shared key 122, but prepare multiple functions 126, which perform fast, different types of transformation, and select a combination of functions determined based on information of the shared key 122, and make the selected functions transform a text multiple times, thereby encrypt the text. Each of the functions is fast, and thus transformation by the entire combination is also fast. Furthermore, since the combination of functions and repetitive count can be changed, future improvement in specification is easy. Moreover, security is high since which functions are applied in what order is unknown.Type: GrantFiled: May 12, 2006Date of Patent: October 8, 2013Assignees: Ochanomizu University, Hiroshima UniversityInventors: Makoto Matsumoto, Takuji Nishimura, Mutsuo Saito, Mariko Hagita
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Publication number: 20130115625Abstract: A protein being the following (A), (B), or (C): (A) a protein represented by the amino acid sequence of SEQ ID NO: 1; (B) a protein represented by an amino acid sequence in which one or a plurality of amino acid is substituted, deleted, inserted or added in the amino acid sequence of SEQ ID NO: 1, the protein having binding activity specific for a mixture of a sphingolipid and cholesterol; or (C) a protein represented by an amino acid sequence being at least 70% identical to the amino acid sequence of SEQ ID NO: 1.Type: ApplicationFiled: May 13, 2011Publication date: May 9, 2013Applicants: RIKEN, YUKIGUNI MAITAKE CO., LTD., OCHANOMIZU UNIVERSITYInventors: Toshihide Kobayashi, Tetsuyuki Kobayashi, Kozo Nishibori, Atsushi Kurahashi, Fumihiro Fujimori
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Publication number: 20130102499Abstract: An object is to provide a means which is useful for the development of an anti-malaria agent. It was found that a mitochondrial DNA polymerase of falciparum malaria shows a bivalent iron ion requirement. Thus, disclosed is a method for measuring the activity of a DNA polymerase, including the steps of: (1) incubating a solution containing a bivalent iron ion, a mitochondrial DNA polymerase of falciparum malaria, template DNA, and at least one deoxyribonucleoside triphosphate or deoxyribonucleoside triphosphate derivative; (2) detecting the synthesized double-stranded DNA; and (3) calculating the activity of the DNA polymerase from the result of the detection carried out in step (2).Type: ApplicationFiled: June 17, 2011Publication date: April 25, 2013Applicants: OCHANOMIZU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITYInventors: Narie Sasaki, Kimiko Murofushi, Katsura Maeda
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Patent number: 8017597Abstract: An object of the present invention is to elucidate an analgesic effect as one of new cPA bioactivities and thus to provide a novel analgesic agent. The present invention provides an analgesic agent which comprises a cyclic phosphatidic acid derivative that is one type of phospholipid.Type: GrantFiled: October 19, 2010Date of Patent: September 13, 2011Assignee: Ochanomizu UniversityInventors: Kimiko Murofushi, Harumi Kanashiki
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Publication number: 20110182479Abstract: To provide a detection device capable of, e.g., obtaining a list of genes whose expressions are commonly changed in response to administration of a specific drug or drugs, based on consideration of relationship (e.g., interacting relationship among genes) among genes, a list of proteins whose expressions are commonly changed in response to administration of a specific drug or drugs, based on consideration of relationship (e.g., interacting relationship among proteins) among proteins, and a list of users who purchased an identical product or products, based on consideration of relationship (e.g., friendship) among users, and so forth. A graph data obtaining unit (20) obtains graph data indicating a graph including a plurality of vertexes. A vertex data obtaining unit (22) obtains vertex data that correlates an information item to a vertex.Type: ApplicationFiled: October 7, 2009Publication date: July 28, 2011Applicant: OCHANOMIZU UNIVERSITYInventors: Jun Sese, Mio Seki
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Publication number: 20110086820Abstract: An object of the present invention is to elucidate an analgesic effect as one of new cPA bioactivities and thus to provide a novel analgesic agent. The present invention provides an analgesic agent which comprises a cyclic phosphatidic acid derivative that is one type of phospholipid.Type: ApplicationFiled: October 19, 2010Publication date: April 14, 2011Applicant: OCHANOMIZU UNIVERSITYInventors: Kimiko MUROFUSHI, Harumi KANASHIKI
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Publication number: 20090326256Abstract: An object of the present invention is to elucidate an analgesic effect as one of new cPA bioactivities and thus to provide a novel analgesic agent. The present invention provides an analgesic agent which comprises a cyclic phosphatidic acid derivative that is one type of phospholipid.Type: ApplicationFiled: December 25, 2007Publication date: December 31, 2009Applicant: OCHANOMIZU UNIVERSITYInventors: Kimiko Murofushi, Harumi Kanashiki
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Publication number: 20090296928Abstract: The present invention provides a pseudorandom number generating system, an encryption system, and a decryption system. The pseudorandom number generating system of the present invention repeatedly performs simple transformation of a non-secure pseudorandom number sequence that may be generated quickly, and thus may quickly generate a highly secure pseudorandom number sequence having a long period. In addition, the encryption system and the decryption system of the present invention do not generate a large encryption function difficult to be deciphered based on a shared key 122, but prepare multiple functions 126, which perform fast, different types of transformation, and select a combination of functions determined based on information of the shared key 122, and make the selected functions transform a text multiple times, thereby encrypt the text. Each of the functions is basically fast, and thus transformation by the entire combination is also fast.Type: ApplicationFiled: May 12, 2006Publication date: December 3, 2009Applicant: OCHANOMIZU UNIVERSITYInventors: Makoto Matsumoto, Takuji Nishimura, Mutsuo Saito, Mariko Hagita