Patents Assigned to of Oregon State
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Publication number: 20250073713Abstract: This disclosure is directed to devices for the separation of mixtures of fluid phases. In some aspects of the disclosure, the separation device comprises an angled capillary cell. In other aspects, the separation device comprises a plurality of angled capillary cells operating in parallel. In some aspects of the disclosure, the separation device may be monolithically formed by an additive manufacturing process, such as three-dimensional printing. In some aspects of the disclosure, the separation device may function independently of gravitational direction, and without the use of filters.Type: ApplicationFiled: August 30, 2024Publication date: March 6, 2025Applicants: Oregon State University, University of Pittsburgh - Of the Commonwealth System of Higher EducationInventors: Goran Jovanovic, Francis Chukwunta, Matthew Coblyn, Lucas Freiberg, Jad Touma, Aigerim Baimoldina, Lei Li, Yihan Song, Bingchen Wang, Fan Yang
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Publication number: 20250073223Abstract: A nanoparticle for delivering an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor to a subject and methods for treating inflamed tissue in a subject using the nanoparticle.Type: ApplicationFiled: September 3, 2024Publication date: March 6, 2025Applicants: Oregon State University, Oregon Health & Science UniversityInventors: Oleh Taratula, Youngrong Park, Olena Taratula, Tetiana Korzun, Daniel L. Marks
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Publication number: 20250051179Abstract: Novel compounds having a thortveitite-related structure are disclosed. The compounds may be colored and may be useful as pigments. The compounds are durable with respect to an acid stability test that indicates that the pigments will not substantially change color when exposed to weak acids, such as rain. The compounds disclosed herein typically inexpensive to synthesize from earth-abundant, environmentally-friendly elements or minerals, and therefore are advantageous over existing pigments in the art.Type: ApplicationFiled: October 28, 2024Publication date: February 13, 2025Applicant: Oregon State UniversityInventors: Munirpallam A. Subramanian, Jun Li, Yi-Chia Lin
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Publication number: 20250034510Abstract: Disclosed herein is a loading apparatus for restoration and/or cryopreservation of biological materials, a system comprising the same, as well as a method for using the loading apparatus and/or system to restore and/or cryopreserve biological materials. The disclosed loading apparatus and method for using the same focuses on utilizing cycles of applying and removing a load (e.g., tension and/or compression pressure) applied to the biological material that facilitate free-swelling of the biological material back to its natural state without the applied load, wherein the free-swelling promotes dispersion of a cryopreservation agent, therapeutic agent, restoration agent, or a combination thereof throughout the surface area of the biological material.Type: ApplicationFiled: July 31, 2023Publication date: January 30, 2025Applicant: Oregon State UniversityInventors: Morgan Giers, Ward Shalash, Adam Higgins
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Patent number: 12209240Abstract: Provided are antisense oligomers targeted against bacterial mRNAs and other macromolecules associated with a biochemical pathway and/or cellular process, and related compositions and methods of using the oligomers and compositions to treat an infected mammalian subject, for example, as primary antimicrobials or as adjunctive therapies with classic antimicrobials.Type: GrantFiled: October 12, 2021Date of Patent: January 28, 2025Assignees: Board of Regents, The University of Texas System, Oregon State UniversityInventors: David Greenberg, Bruce L. Geller
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Publication number: 20250020478Abstract: Briefly, embodiments, such as estimating energy utilization based at least in part on estimated regenerative energy production to select one or more preferred routes for an electric vehicle out of a network of routes, for example, are described.Type: ApplicationFiled: July 10, 2023Publication date: January 16, 2025Applicant: Oregon State UniversityInventor: David Hamilton
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Publication number: 20250004146Abstract: A method is provided to reduce the counting times in radiation detection systems using machine learning, wherein the method comprises: receiving output data from a detector which is to detect a target material from a target body; analyzing the output data; identifying a material of interest from the analyzed output data; and controlling a source of the target material to prevent the source from harming the target body. An apparatus is also provided which comprises: a detector to detect radiation and to provide an output data in real-time; and a processor coupled to the detector, wherein the processor is to: receive the output data; analyze the output data; identify a material of interest from the analyzed output data; and control a source of the target material.Type: ApplicationFiled: November 7, 2022Publication date: January 2, 2025Applicants: Oregon State University, Georgetown UniversityInventors: Ophir Frieder, Steven Richard Reese, Jessica Ryan Curtis
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Publication number: 20240425467Abstract: Tetrazine non-canonical amino acids, methods for genetic encoding proteins and polypeptides using the tetrazine amino acids, proteins and polypeptides comprising the tetrazine amino acids, and compositions comprising the proteins and polypeptides having at least one post-translational modification thereof comprising in vivo reaction with the incorporated tetrazine amino acid and a second molecule.Type: ApplicationFiled: August 26, 2024Publication date: December 26, 2024Applicant: OREGON STATE UNIVERSITYInventors: Ryan A. Mehl, Robert Blizzard
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Patent number: 12172948Abstract: Multifunctional dendritic molecular probes that selectively detect Cu2+ ions via potentiometric and fluorometric techniques with low detection limits are disclosed. The selective and reversible binding of the molecules with the Cu2+ ion was used to make solid-state microsensors by incorporating the molecular probes into the carbon-based membranes as an ionophore for Cu (II).Type: GrantFiled: November 12, 2021Date of Patent: December 24, 2024Assignee: Oregon State UniversityInventors: Dipankar Koley, Partha Sarathi Sheet
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Publication number: 20240412881Abstract: A machine-learning tool learns from sensors' data of a nuclear reactor at steady state and maps them to controls of the nuclear reactor. The tool learns all given ranges of normal operation and responses for corrective measures. The tool may train another learning tool (or the same tool) that forecasts the behavior of the reactor based on real-time changes (e.g., every 10 seconds). The tool implements an optimization technique for differing half-life materials to be placed in the reactor. The tool maximizes isotope production based on optimal controls of the reactor.Type: ApplicationFiled: August 19, 2024Publication date: December 12, 2024Applicants: Oregon State University, Georgetown UniversityInventors: Steven R. Reese, Ophir Frieder, Mario Enrique Gomez Fernandez
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Patent number: 12162035Abstract: A print head comprising nested chambers for in-situ reactant formation is disclosed. The print head comprises a first chamber nested within a second chamber. The first chamber comprises a first nozzle, the second chamber comprises a second nozzle. The first nozzle is substantially coaxial with the second nozzle. A susceptor to convert electromagnetic energy to heat is within the first chamber. The susceptor comprises one or more openings extending between the upper portion and the lower portion. The susceptor may be heated by induction heating or by optical heating to vaporize a precursor substance within the first chamber. The vapor may react with a reactive gas flowing through the first chamber or expand through a nozzle into a second chamber where the vapor may react with the reactive gas, forming nanoparticles. Patterned films may be written onto a two-dimensional or three-dimensional surfaces.Type: GrantFiled: July 26, 2022Date of Patent: December 10, 2024Assignee: Oregon State UniversityInventors: Chih-hung Chang, Venkata Vinay Krishna Doddapaneni, Yujuan He, Jeffrey Dhas, Brian K. Paul, Somayeh Pasebani, Chuankai Song, Sakineh Abbasi
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Publication number: 20240404653Abstract: A processing workflow centered on machine-learning algorithms that identifies a number of chemical features that can best distinguish the presence or absence of a chemical source. These chemical features are a chemical fingerprint that is unique to each source. The analysis workflow is rapid (e.g., fingerprints can be generated in minutes). The analysis workflow has wide-ranging applications such as detecting markers of pollution sources in rivers and fish tissues, forest pathogen outbreaks, and hard-to-diagnose diseases.Type: ApplicationFiled: August 12, 2024Publication date: December 5, 2024Applicant: Oregon State UniversityInventor: Gerrad Jones
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Publication number: 20240391961Abstract: Embodiments of the present disclosure provide compositions and methods for biosynthesizing a stable, functional mimic of phosphoserine. The compositions and methods described herein genetically program a host cell to express a biosynthetic pathway that can synthesize the amino acid, 2-amino-4-phosphobobutyric acid, that is a non-hydrolyzable phosphoserine (nhpSer) because it contains a carbon-phosphorus, e.g., phosphonate, bond. In one embodiment the genetically programed cells express the enzymes of a pathway from a Streptomyces bacterium. In some embodiments, nhpSer is translationally incorporated into protein of interest at one or more programmed UAG amber codons using Genetic Code Expansion (GCE) technology.Type: ApplicationFiled: August 25, 2022Publication date: November 28, 2024Applicant: Oregon State UniversityInventors: Richard B. Cooley, Ryan A. Mehl, Phillip Zhu
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Patent number: 12133536Abstract: Disclosed herein are embodiments of a coating composition comprising cellulose nanomaterials and emulsion systems. The coating compositions provide improved moisture barrier and wettability onto fruit surfaces and can control physiological activity and enhance storability of food products, such as fruits during ambient storage. Also disclosed herein are embodiments of dried and substantially dried coatings, films, products made with the coating compositions, and methods of making and using the coating compositions described herein.Type: GrantFiled: July 30, 2019Date of Patent: November 5, 2024Assignee: Oregon State UniversityInventors: Jooyeoun Jung, John Simonsen, Yanyun Zhao
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Publication number: 20240352605Abstract: A method for making a catalyst comprises providing an initial compound having a perovskite lattice structure according to formula I M1M2M3O3 ??FORMULA I, where M1 is about 1 relative elemental ratio strontium (Sr); M2 is from greater than 0 to 0.7 relative elemental ratio and is selected from cobalt (Co), scandium (Sc), iron (Fe), nickel (Ni), and titanium (Ti); and M3 is 0.3 to 0.6 relative elemental ratio iridium (Ir). Initial exemplary compounds include SrSc0.5Ir0.5O3 (SSI) and SrCo0.5Ir0.5O3 (SCI). M1 and/or M2 cations are selectively leached from the initial compound to produce a catalyst having substantially increased catalytic performance. Cycling SSI or SCI in an acid produces SSI-H or SCI-H; cycling SSI or SCI in a base produces SSI-OH or SCI-OH. Dual-site metal leaching induced catalytic activity improvement by about 2 orders of magnitude, making reconstructed SrCo0.5Ir0.5O3 among the best-known catalysts for water oxidation in an acidic condition.Type: ApplicationFiled: June 4, 2024Publication date: October 24, 2024Applicants: Oregon State University, Nanyang Technological UniversityInventors: Yubo Chen, Zhenxing Feng, Maoyu Wang, Zhichuan Xu
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Publication number: 20240356575Abstract: A wireless sensor network is described. The wireless sensor network comprises an interrogator transceiver operable to transmit a first wireless signal at a first RF frequency and to receive a second wireless signal at a second RF frequency to and from a wireless sensor node embedded within a medium. The medium comprises one or more dielectric materials. The wireless sensor node is interrogatable by the interrogator transceiver. The wireless sensor node is operable to receive the first wireless signal at the first RF frequency from the interrogator transceiver and to transmit the second wireless signal at the second RF frequency to the interrogator transceiver. A processor is coupled to a circuit within the interrogator transceiver. The circuit is operable to measure a power level of a received signal, and the processor is operable to correlate the power level of the received signal to a composition of the medium.Type: ApplicationFiled: April 15, 2024Publication date: October 24, 2024Applicant: Oregon State UniversityInventors: Thomas McCrea Weller, Ismail Uluer, Jeff Frolik
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Publication number: 20240343760Abstract: Disclosed herein are peptides useful for targeting the retina, and may be useful for targeting specific cells in the retina. The peptides may have a Formula I or V: R1—X1—X2—(X3)n—X4—X5—X6—X7—R2?? Formula I R1-Asn-Val-Ser-Ala-Tyr-Pro-Thr-R2?? Formula V. Also disclosed are conjugates and compositions comprising the peptides. The compositions may comprise a desired agent to be delivered to the retina, such as a therapeutic agent and/or an imaging agent. Methods for administering the peptide, conjugates, and/or composition to a subject also are disclosed.Type: ApplicationFiled: June 13, 2024Publication date: October 17, 2024Applicants: Oregon State University, Oregon Health & Science UniversityInventors: Marco Herrera, Gaurav Sahay, Renee Ryals
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Publication number: 20240337477Abstract: Described herein is a magnetic dendrometer having a frame, a spring-tension mechanism, and a magnet for moving together with the spring-tension mechanism. A magnetic sensor is attached to the frame. The magnetic sensor senses the linear motion of the magnet. This linear motion translates to trackable fluctuations in magnetic field. The magnetic fluctuations are converted to electrical signals by the magnetic sensor. A spring is attached to a free-floating wishbone-style component. The free-floating wishbone-style component is couped to a slider which has an adjustable, single-contact point with a target (e.g., a vine, a branch, etc.). The frame is a stationary frame that carries the magnetic sensor. The frame connected via the spring to the wishbone/slider combination cooperates with each other for providing linear motion to extend or contract the spring in length directions. The length variations of the dendrometer spring are converted to linear motion of the magnet and then into electronic signals.Type: ApplicationFiled: June 14, 2024Publication date: October 10, 2024Applicant: Oregon State UniversityInventors: Cameron Clonch, Bryson Goto, Mark Huynh, John Selker, Chet Udell
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Patent number: 12106865Abstract: A machine-learning tool learns from sensors' data of a nuclear reactor at steady state and maps them to controls of the nuclear reactor. The tool learns all given ranges of normal operation and responses for corrective measures. The tool may train another learning tool (or the same tool) that forecasts the behavior of the reactor based on real-time changes (e.g., every 10 seconds). The tool implements an optimization technique for differing half-life materials to be placed in the reactor. The tool maximizes isotope production based on optimal controls of the reactor.Type: GrantFiled: April 21, 2021Date of Patent: October 1, 2024Assignee: Oregon State UniversityInventors: Steven R. Reese, Ophir Frieder, Mario Enrique Gomez Fernandez
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Patent number: PP36388Abstract: A new and distinct Styrax japonicus plant named ‘ORSTSTYx1’ is disclosed, characterized by its strict weeping habit, purple foliage, pink flowers, and vigorous growth.Type: GrantFiled: August 31, 2023Date of Patent: January 14, 2025Assignee: Oregon State UniversityInventor: Ryan N. Contreras