Patents Assigned to OHM ONCOLOGY
  • METHOD OF SYNTHESIS OF COMPOUND FOR DUAL INHIBITION OF JAK2 AND BET
    Publication number: 20220315594
    Abstract: Embodiments of the invention include quinoline compounds and methods of synthesis. Ohm-581 has demonstrated dual inhibition of JAK2 and BET and acts as a therapeutic agent for micosis fungoides (MF) and other hematologic malignancies. Embodiments also include an efficient process for the preparation of Ohm-581 and pharmaceutically acceptable salts. The process is suited for large-scale production of quinoline compounds including Ohm-581.
    Type: Application
    Filed: August 9, 2020
    Publication date: October 6, 2022
    Applicant: OHM ONCOLOGY
    Inventors: Ram Shankar Upadhayaya, Murali Krishna Ukkalam, K Narasimha Sarma