Patents Assigned to OISIN BIOTECHNOLOGIES
  • Fusogenic lipid nanoparticles for target cell-specific production of a therapeutic protein
    Patent number: 11603543
    Abstract: Provided nucleic acid-based expression construct for the target cell-specific production of a therapeutic protein, such as a pro-apoptotic protein, within a target cell, including a target cell that is associated with aging, disease, or other condition, in particular a target cell that is a senescent cell or a cancer cell.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: March 14, 2023
    Assignee: OISIN BIOTECHNOLOGIES, INC.
    Inventors: Matthew Rein Scholz, John David Lewis, Gary Charles Hudson
  • Expression constructs, fusogenic lipid-based nanoparticles and methods of use thereof
    Patent number: 11525146
    Abstract: Provided nucleic acid-based expression construct for the target cell-specific production of a therapeutic protein, such as a pro-apoptotic protein, within a target cell, including a target cell that is associated with aging, disease, or other condition, in particular a target cell that is a senescent cell or a cancer cell.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: December 13, 2022
    Assignee: OISIN BIOTECHNOLOGIES, INC.
    Inventor: Matthew Rein Scholz
  • FUSOGENIC LIPID NANOPARTICLES AND METHODS FOR THE MANUFACTURE AND USE THEREOF FOR THE TARGET CELL-SPECIFIC PRODUCTION OF A THERAPEUTIC PROTEIN AND FOR THE TREATMENT OF A DISEASE, CONDITION, OR DISORDER ASSOCIATED WITH A TARGET CELL
    Publication number: 20200109419
    Abstract: Provided nucleic acid-based expression construct for the target cell-specific production of a therapeutic protein, such as a pro-apoptotic protein, within a target cell, including a target cell that is associated with aging, disease, or other condition, in particular a target cell that is a senescent cell or a cancer cell.
    Type: Application
    Filed: April 18, 2019
    Publication date: April 9, 2020
    Applicant: Oisin Biotechnologies, Inc.
    Inventor: Matthew Rein Scholz
  • EXPRESSION CONSTRUCTS AND SYSTEMS FOR SYSTEMIC AND NON-SPECIFIC IN VIVO DELIVERY OF A NUCLEIC ACID TO HUMAN CELLS AND TRANSIENT TARGET CELL-SPECIFIC PRODUCTION OF A THERAPEUTIC PROTEIN
    Publication number: 20200009268
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 9, 2020
    Applicant: Oisin Biotechnologies, Inc.
    Inventor: Matthew R Scholz
  • FUSOGENIC LIPID NANOPARTICLES AND METHODS FOR THE MANUFACTURE AND USE THEREOF FOR THE TARGET CELL-SPECIFIC PRODUCTION OF A THERAPEUTIC PROTEIN AND FOR THE TREATMENT OF A DISEASE, CONDITION, OR DISORDER ASSOCIATED WITH A TARGET CELL
    Publication number: 20190330657
    Abstract: Provided nucleic acid-based expression construct for the target cell-specific production of a therapeutic protein, such as a pro-apoptotic protein, within a target cell, including a target cell that is associated with aging, disease, or other condition, in particular a target cell that is a senescent cell or a cancer cell.
    Type: Application
    Filed: January 9, 2018
    Publication date: October 31, 2019
    Applicant: Oisin Biotechnologies, Inc.
    Inventor: Matthew R Scholz
  • SYSTEMS AND METHODS FOR THE TARGETED PRODUCTION OF A THERAPEUTIC PROTEIN WITHIN A TARGET CELL
    Publication number: 20160051700
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: March 24, 2014
    Publication date: February 25, 2016
    Applicant: OISIN BIOTECHNOLOGIES
    Inventor: Matthew R Scholz
  • SYSTEMS AND METHODS FOR THE TARGETED PRODUCTION OF A THERAPEUTIC PROTEIN WITHIN A TARGET CELL
    Publication number: 20160010110
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Applicant: OISIN BIOTECHNOLOGIES
    Inventor: Matthew R. Scholz