Abstract: The present disclosure provides a compound that is useful for the treatment and prophylaxis of rabies. The present disclosure provides a compound represented by formula XXIF or formula XXIB: wherein R1, R2A, R2B, R3, and R4 are defined in the specification, a solvent, or a pharmaceutically acceptable salt thereof, use of such a compound, solvate, or pharmaceutically acceptable salt thereof for the treatment or prophylaxis of rabies and cancer, a pharmaceutical composition comprising such a compound, solvate, or pharmaceutically acceptable salt thereof, and a method for the treatment or prophylaxis of rabies and cancer using the same.

Abstract: This invention provides a simple analysis method by a PCR method that simultaneously performs, in a single container, separating nucleic acid of pathogens contained in a tissue fragment and preparing a PCR buffer solution, and a kit used for the analysis method. A method for detecting a pathogen includes: (1) obtaining a liquid specimen mixture by adding a tissue fragment containing a pathogen to a PCR buffer solution containing a proteolytic enzyme; (2) heating the liquid specimen mixture at a first temperature; (3) further heating at a second temperature; (4) performing PCR by adding a portion of the liquid mixture obtained in (3) above to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated in (4) above.

Abstract: The drive of direct-heat-supply type reforming of hydrocarbon at ordinary temperature is necessary in order to realize a self-sustaining, on-site reforming type fuel cell system which does not necessitate the supply of energy from the outside. According to the invention, an oxide, CeO2 or Pr6O11, or a Ce/Zr or Ce/Zr/Y double oxide is used as the oxide containing a rare earth element capable of changing the oxidation number with an active metal and oxygen defects are introduced into the oxide or double oxide by activating the oxide or double oxide with a reducing gas at high temperature. When a reaction gas containing hydrocarbon and oxygen is passed though the catalyst at low temperature, the oxygen defects react with oxygen and thereby return to the original oxide.

Abstract: When a commercial power supply E operates normally, converter sections PFC1, PFC2 connected in parallel to each other can operate to approximate the input current from the commercial power supply E to the waveform and phase of the input voltage to correct a power factor while supplying stabilized output voltages Vo1, Vo2 to a load. When the voltage of the commercial power supply E drops, the smoothing capacitor Co1 operates as an input power supply to power the converter section PFC2, which allows the smoothing capacitor Co2 to supply the stabilized output voltage Vo2 to the load.

Abstract: To provide a power supply apparatus that can supply a large current and a small current to a load circuit in a switchable manner, with a minimum circuit scale and an efficient use of electronic devices and elements contained in conventionally used power supply apparatuses.

Abstract: To eliminate the problem that a magnetic deflection is caused in a transformer even when a coupled inductor converter is in a stationary operation state, provided is a DC-DC converter including a first series circuit portion formed by a first switching transistor, a first capacitor, a first inductor, and a second capacitor which are connected to a DC power in series in this order, and a second series circuit portion formed by a second switching transistor and a second inductor which are connected in series in this order, the second series circuit portion is connected in parallel to the first capacitor and the first inductor, and the first inductor and the second inductor constitute a coupled inductor having a plurality of windings and a common magnetic core.