Abstract: A magnetic cluster includes a (CoC2)4 tetragonal structure with Co—C2—Co bonds, and a molecular formula (CoC2)x (x: natural number).

Abstract: An object of the present invention is to provide a null mutant non-human animal showing salt intake behavior similar to that of wild-type animals under water-sufficient conditions and showing much more intakes of hypertonic saline compared with wild-type animals under water- and salt-depleted conditions, for example, an Nav2 gene-deficient non-human animal, which is useful as a model animal of excessive salt intake experiments. The object will be attained by following process: mouse genomic libraries are screened with rat NaG cDNA as a probe, then Nav2 gene of genomic DNA is isolated, and a targeting vector is constructed by inserting marker gene such as neo gene into the exon of Nav2. After thus constructed targeting vector is induced to ES cells, homologously recombined ES cells are selected, then germ line chimeric mice are constructed with this ES cells strain, and they are hybridized with the wild-type mice and heterozygous mutant mice are obtained.

Abstract: A biosensor protein comprising (1) and (2) below: (1) a modified fluorescent protein which is obtained by cleaving amino acid sequence of green fluorescent protein or its derivative in the vicinity of a hotspot amino acid residue which affects the fluorescence property, and modifying the structure of the green fluorescent protein or its derivative, and (2) one or more functional molecules which are capable of transmitting their conformational changes to the modified fluorescent protein to cause a conformational change of the modified fluorescent protein, thereby altering the fluorescence property of the modified fluorescent protein.

Abstract: A magnetic cluster includes a (CoC2)4 tetragonal structure with Co—C2—Co bonds, and a molecular formula (CoC2)x (x: natural number).

Abstract: With rotating and translating a rotation-translation drum installed in a vacuum chamber of a mass spectrometry interface to constitute a mass spectro-meter, a liquid sample incorporating a dissolved substance to be analyzed in its mass is emitted for the drum from a sample supplying nozzle of the mass spectrometry interface, and the dissolved substance is isolated as a spiral filament on the drum. Then, a laser beam is irradiated onto the filament from a laser source via a laser beam inlet situated at the vacuum chamber and thereby, the dissolved substance is ionized without exposing to the air.

Abstract: A polypeptide having an amino acid sequence (a) or (b) given below. (a) a polypeptide having an amino acid sequence shown by amino acid Nos. 1 to 689 in Sequence Listing No. 2 and (b) a polypeptide which has activity of a progestogen receptor and which is a derivative obtained by way of deletion, substitution, addition or insertion of a part of the amino acid sequence in the above (a). Corresponding DNA gene and transgenic cell as well as a method for detecting a disruptor using this transgenic cell are also disclosed.

Abstract: A transgenic cell is disclosed, where includes a culture cell, and an androgen receptor-expression vector and a foreign reporter gene introduced into said culture cell, said foreign reporter gene having a gene promoter, which is a target of said androgen and an androgen receptor, inserted therein. This transgenic cell is used for detecting a disrupter in a material to be examined through examining the expression of the foreign reporter gene when being brought into contact with the material.

Abstract: There is disclosed a chiral molecular magnet having characteristics exhibiting a monocrystal, a magnetic property, an optical activity, a transparent color and a relatively high transition temperature. This chiral molecular magnet is formed of a monocrystal represented by a general formula [Mn(L)]3[Cr(CN)6]2.4H2O (wherein L is optically active (R or S)-1,2-diamines and derivatives thereof or optically active (R or S)-1,3-diamines and derivatives thereof).