Patents Assigned to Okinawa Institute of Science and Technology Graduate University
  • Patent number: 9684764
    Abstract: In a plurality of data analysis apparatuses communicatively coupled to one another, a database is accessed at a given access level. Based on the data acquired from the database, an application program is executed to perform data analysis. Communication control is performed to allow transmission and reception of a data analysis result with respect to another data analysis apparatus at a different access level.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: June 20, 2017
    Assignees: Okinawa Institute of Science and Technology Graduate University, SBX Corporation, The Systems Biology Institute
    Inventors: Hiroaki Kitano, Samik Ghosh, Yukiko Matsuoka
  • Publication number: 20150278451
    Abstract: In a plurality of data analysis apparatuses communicatively coupled to one another, a database is accessed at a given access level. Based on the data acquired from the database, an application program is executed to perform data analysis. Communication control is performed to allow transmission and reception of a data analysis result with respect to another data analysis apparatus at a different access level.
    Type: Application
    Filed: November 7, 2013
    Publication date: October 1, 2015
    Applicants: Okinawa Institute of Science and Technology Graduate University, SBX Corporation, The Systems Biology Institute
    Inventors: Hiroaki Kitano, Samik Ghosh, Yukiko Matsuoka
  • Patent number: 9137122
    Abstract: The present invention involves retrieving edges that do not constitute a designated network model which is a network model designated by a user and are linked to nodes that constitute the designated network model, displaying retrieval results that include the retrieved edges and network model IDs corresponding to the edges in a selectable manner, and generating an integrated network model in which, when the retrieval results are selected by the user, the edges that are included in the selected retrieval results and the nodes that do not constitute the designated network model and are linked to the edges, are integrated into the designated network model.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: September 15, 2015
    Assignees: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY, The Systems Biology Institute
    Inventors: Hiroaki Kitano, Yukiko Matsuoka, Samik Ghosh
  • Publication number: 20150169822
    Abstract: The present invention acquires compound structure data and candidate protein structure data on a candidate protein serving as a candidate for interaction with the compound. The present invention calculates a binding strength between the candidate protein and the compound using a docking simulation method, determines a predicted binding strength corresponding to the binding strength predicted by making a comprehensive evaluation of the binding strength, and determines a predicted protein corresponding to the candidate protein predicted to interact with the compound. The present invention calculates an interaction strength using a binding strength simulation method and determines a predicted interaction strength corresponding to the interaction strength predicted by making the comprehensive evaluation of the interaction strength.
    Type: Application
    Filed: June 13, 2013
    Publication date: June 18, 2015
    Applicants: Okinawa Institute of Science and Technology Graduate University, The Systems Biology Institute
    Inventors: Hiroaki Kitano, Kun-yi Hsin, Samik Ghosh
  • Publication number: 20150024491
    Abstract: An object of the present invention is to develop and provide a method for producing a neuron model having reproduced in vivo properties by improving a cell culture medium composition and a cell culture medium composition necessary for the production of such neuron model. According to the present invention, cell culture is carried out in vitro using a medium for producing in vivo-like and enhanced synaptogenesis neuron model supplemented with a medium supplement for producing in vivo-like and enhanced synaptogenesis neuron model comprising any or any combination of NT-3, potassium or a salt thereof, and FGF2.
    Type: Application
    Filed: March 27, 2012
    Publication date: January 22, 2015
    Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY
    Inventors: Dimitar Ivanov Dimitrov, Laurent Elie Guillaud, Zacharie Mehdi Francois Taoufiq, Tomoyuki Takahashi
  • Publication number: 20130185644
    Abstract: The present invention involves retrieving edges that do not constitute a designated network model which is a network model designated by a user and are linked to nodes that constitute the designated network model, displaying retrieval results that include the retrieved edges and network model IDs corresponding to the edges in a selectable manner, and generating an integrated network model in which, when the retrieval results are selected by the user, the edges that are included in the selected retrieval results and the nodes that do not constitute the designated network model and are linked to the edges, are integrated into the designated network model.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 18, 2013
    Applicants: The Systems Biology Institute, OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY
    Inventors: Hiroaki Kitano, Yukiko Matsuoka, Samik Ghosh
  • Publication number: 20130079900
    Abstract: The present invention sets, for each cells or each condition, a production output of the cells or the biomass based on the measured data and a variable indicating an extent of variation of the production output, calculates a variable range of the production output and the variable in case of combining the multiple cells or conditions based on the production output and the variable set, and calculates an optimum combination within the variable range by using an optimization method.
    Type: Application
    Filed: March 31, 2011
    Publication date: March 28, 2013
    Applicants: The Systems Biology Institute, Okinawa Institute of Science and Technology Graduate University
    Inventor: Hiroaki Kitano