Patents Assigned to Olea Medical
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Publication number: 20230288513Abstract: The invention relates to a method for carrying out post-processing on a first set of samples measuring the magnitude of a WASAB1 signal delivered by a magnetic-resonance medical-imaging apparatus. Such a method comprises a step of detecting the samples of a first set Z, for which samples the respective polarities of the values of the measured signal are known, and of constructing a second set Y of “polarised” samples. Such a method further comprises a step of fitting a determined model to said second set Y, the two parameters of the determined model describing the static magnetic field B0 and excitation magnetic field B1 of the magnetic-resonance medical-imaging apparatus, respectively, and of producing an estimation of the parameters B0 and B1 of the model. Such a method relates to any magnetic-resonance-imaging application in which a correction for inhomogeneities in the fields B0 and B1 is required.Type: ApplicationFiled: October 13, 2021Publication date: September 14, 2023Applicant: OLEA MEDICALInventors: Benoît GY, Christos PAPAGEORGAKIS, Stefano CASAGRANDA, Timothé BOUTELIER
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Publication number: 20230225630Abstract: A system and method for denoising experimental data originating from multiple acquisitions by a magnetic resonance imaging device, by analysis of selected principal components, to obtain a better compromise between the efficiency of the denoising and retention of the relevant information in the experimental data under consideration during their reconstruction to produce denoised experimental data. A selection criterion is based on the informative indicators quantifying the spatial information contained in images of scores associated with said principal components. The invention also provides for the capability to apply an adaptive filtering excluding the persistent spatial noise associated with each component selected.Type: ApplicationFiled: March 16, 2023Publication date: July 20, 2023Applicant: OLEA MEDICALInventors: Stefano CASAGRANDA, Christos PAPAGEORGAKIS, Mauro ZUCCHELLI
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Publication number: 20230214999Abstract: The invention relates to a system and method for quantifying a novel biomarker of the tissue activity of a human or animal organ. By way of preferred application, such a biomarker describes the diffusivity of biological fluids in living tissues in the form of a novel indicator of the diffusion of water molecules in living tissues on the basis of diffusion data resulting from the acquisition of a sequence of images of one or more parts of the body of an animal or human patient. Particularly resistant and stable with respect to noise present in the medical imaging signals from which the experimental data stem, the novel biomarker is relevant in a large number of applications including, inexhaustively, the analysis and/or monitoring of cancers, or the assessment of strokes.Type: ApplicationFiled: May 18, 2021Publication date: July 6, 2023Applicant: OLEA MEDICALInventors: Romain SUDRE, Julien ROUYER, Timothé BOUTELIER, Christophe AVARE
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Publication number: 20190246915Abstract: The invention concerns a system and method for reconstructing a physiological signal of an artery/tissue/vein system of an organ in a surface space. Said method is implemented by processing means of a processing unit of a functional imaging analysis system, and comprises a step for reconstructing said physiological signal from a piece of experimental data of a region of interest comprising an elementary volume—called a voxel—of said organ and a surface mesh describing said surface space. The invention differs from known methods in particular in terms of the high accuracy of same and the robustness thereof to noise.Type: ApplicationFiled: September 8, 2017Publication date: August 15, 2019Applicants: Olea Medical, Universite d'Aix-Marseille, Centre National de la Recherche ScientifiqueInventors: Lucie THIEBAUT LONJARET, Christine BAKHOUS, Olivier COULON, Sylvain TAKERKART
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Patent number: 9983287Abstract: The invention relates to a system and method for estimating a quantity of interest from perfusion data resulting from the acquisition of a plurality of a patient volumes or stations. Such a method may include a step for triggering the output of said quantity of interest in the form of a consolidated map by means of an adapted man-machine interface.Type: GrantFiled: May 4, 2016Date of Patent: May 29, 2018Assignee: OLEA MEDICALInventors: Fayçal Djeridane, Timothé Boutelier
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Publication number: 20180095152Abstract: A system and a method for producing an estimation of a physiological parameter of an elementary volume, termed a voxel, of an organ is implemented by a processing unit of a magnetic resonance imaging analysis system. The method includes a step for estimating the physiological parameter, the step for estimating the physiological parameter including producing the estimated value of the physiological parameter on the basis of the respective prior estimations of first and second physiological parameters.Type: ApplicationFiled: March 22, 2016Publication date: April 5, 2018Applicant: OLEA MEDICALInventors: Bruno TRIAIRE, Timothé BOUTELIER
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Publication number: 20160245889Abstract: The invention relates to a system and method for estimating a quantity of interest from perfusion data resulting from the acquisition of a plurality of a patient volumes or stations. Such a method may include a step for triggering the output of said quantity of interest in the form of a consolidated map by means of an adapted man-machine interface.Type: ApplicationFiled: May 4, 2016Publication date: August 25, 2016Applicant: OLEA MEDICALInventors: Fayçal DJERIDANE, Timothé BOUTELIER
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Patent number: 9311702Abstract: The invention relates to a system and a method for estimating a quantity of interest of a dynamic artery/tissue/vein system of an elementary volume—referred to as a voxel—of an organ based on medical images according to the methods referred to as oSVD or cSVD. The invention discloses two embodiments which are distinguished by the execution time necessary in order to produce the estimate of said quantity of interest and enable a therapeutic diagnosis including in an emergency situation.Type: GrantFiled: August 24, 2012Date of Patent: April 12, 2016Assignee: OLEA MEDICALInventor: Fabrice Pautot
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Patent number: 9208557Abstract: The invention relate to a system and a process for estimating hemodynamic parameters by applying soft probabilistic methods to perfusion imaging. Such a process also makes it possible to estimate arterial input or complementary distribution functions and therefore more generally any quantity of interest. The invention stands out in particular from the known processes in that it requires the introduction, a priori, of soft information of physiological or hemodynamic nature without constraining of forcing the desired estimation through arbitrary or undesirable hypotheses.Type: GrantFiled: October 11, 2011Date of Patent: December 8, 2015Assignee: OLEA MEDICALInventor: Fabrice Pautot
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Publication number: 20150248758Abstract: This invention relates to a method for producing and outputting a quantity of interest relative to a flow within a polyhedral space of a kinematic system, advantageously implemented by a processing unit of a tomographic imaging system. The invention applies, specifically but not limited, to the estimation of volumetric flows or plasma, interstitial or compound volumes relative to the flow of a contrast agent within an organ by permeability or perfusion imaging.Type: ApplicationFiled: October 7, 2013Publication date: September 3, 2015Applicant: OLEA MEDICALInventor: Fabrice Pautot
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Patent number: 9123100Abstract: A computer-readable storage medium comprising computer-readable program code stored thereon which, when interpreted by a computing apparatus, causes the computing apparatus to implement an image processing tool for processing a plurality of biological images arranged in a plurality of image series wherein certain biological images across different image series have a predefined correspondence with one another.Type: GrantFiled: November 1, 2012Date of Patent: September 1, 2015Assignee: OLEA MEDICALInventor: Faycal Djeridane
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Publication number: 20140219532Abstract: The invention relates to a system and a method for estimating a quantity of interest of a dynamic artery/tissue/vein system of an elementary volume—referred to as a voxel—of an organ based on medical images according to the methods referred to as oSVD or cSVD. The invention discloses two embodiments which are distinguished by the execution time necessary in order to produce the estimate of said quantity of interest and enable a therapeutic diagnosis including in an emergency situation.Type: ApplicationFiled: August 24, 2012Publication date: August 7, 2014Applicant: OLEA MEDICALInventor: Fabrice Pautot
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Patent number: 8792701Abstract: The invention relates to a method for estimating haemodynamic perfusion parameters of an elementary volume—termed a voxel—of an organ, from perfusion signals by jointly estimating the parameters of an optionally limited comprehensive perfusion model. The invention moreover relates to a processing unit of a perfusion imaging analysis system, adapted for carrying out such a method and for delivering the estimated parameters according to an appropriate format to a human-machine interface able to represent said estimated parameters for a user.Type: GrantFiled: June 1, 2010Date of Patent: July 29, 2014Assignee: Olea MedicalInventors: Fayçal Djeridane, Fabrice Pautot
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Publication number: 20140180146Abstract: A system and a process for representing collateral circulation in voxels of an organ. Arterial tissue delay is estimated from perfusion data by evaluating, according to a Bayesian method, a posterior marginal probability distribution for the arterial tissue delay. The estimated arterial tissue delay of each voxel is estimated relative to a threshold value. An indication of the voxels whose arterial tissue delay values exceed the threshold is displayed on a display device.Type: ApplicationFiled: December 20, 2013Publication date: June 26, 2014Applicant: OLEA MEDICALInventor: François NICOLI
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Publication number: 20130266201Abstract: The invention relate to a system and a process for estimating hemodynamic parameters by applying soft probabilistic methods to perfusion imaging. Such a process also makes it possible to estimate arterial input or complementary distribution functions and therefore more generally any quantity of interest. The invention stands out in particular from the known processes in that it requires the introduction, a priori, of soft information of physiological or hemodynamic nature without constraining of forcing the desired estimation through arbitrary or undesirable hypotheses.Type: ApplicationFiled: October 11, 2011Publication date: October 10, 2013Applicant: Olea MedicalInventor: Fabrice Pautot
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Publication number: 20130058549Abstract: A computer-readable storage medium comprising computer-readable program code stored thereon which, when interpreted by a computing apparatus, causes the computing apparatus to implement an image processing tool for processing a plurality of biological images arranged in a plurality of image series wherein certain biological images across different image series have a predefined correspondence with one another.Type: ApplicationFiled: November 1, 2012Publication date: March 7, 2013Applicant: OLEA MEDICALInventor: Olea Medical
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Patent number: 8320647Abstract: A computer-readable storage medium comprising computer-readable program code stored thereon which, when interpreted by a computing apparatus, causes the computing apparatus to implement an image processing tool for processing a plurality of biological images arranged in a plurality of image series wherein certain biological images across different image series have a predefined correspondence with one another.Type: GrantFiled: March 26, 2008Date of Patent: November 27, 2012Assignee: Olea MedicalInventor: Faycal Djeridane